Krystal Ann Hughes, PharmD, PhD

Dr. Krystal Ann Hughes is an Assistant Professor in the West Virginia University School of Pharmacy and the WVU School of Medicine. She also serves as the Director of Interdisciplinary Pharmacology Education.

Teaching Assistant Professor

Organization:

West Virginia University School of Medicine

Department:

Physiology, Pharmacology & Toxicology

Classification:

Faculty

Director of Interdisciplinary Pharmacology Education, Teaching Assistant Professor

Organization:

West Virginia University School of Pharmacy

Department:

Pharmaceutical Sciences

Classification:

Admin

• PharmD, West Virginia University School of Pharmacy
• MS, Clinical and Translational Science - West Virginia University School of Medicine
• PhD, West Virginia University School of Pharmacy

Delivery of Monomethyl Auristatin E Using Ionizable Lipid Nanoparticles for B‑Cell Acute Lymphoblastic Leukemia Treatment
WH Pentz, KA Hughes, B Misra, SV Nandigama, A Murray, A Samuelson, ...ACS
omega 11 (22), 32321

Development of Novel Carbohydrate-Based Nanoparticles for Precision Drug Delivery
KA Hughes
West Virginia University

Discover Nano
KA Hughes, B Misra, M Maghareh, P Samart, E Nguyen, S Hussain, ...

Flash nanoprecipitation allows easy fabrication of pH-responsive acetalated dextran nanoparticles for intracellular release of payloads
KA Hughes, B Misra, M Maghareh, P Samart, E Nguyen, S Hussain, ...
Discover Nano 19 (4)

Flash nanoprecipitation assisted self-assembly of ionizable lipid nanoparticles for nucleic acid delivery
B Misra, KA Hughes, WH Pentz, P Samart, WJ Geldenhuys, S Bobbala
Nanoscale 16 (14), 6939-6948

Molecular Pathology of Immune Checkpoint Inhibitor-Induced Myocarditis
K Hughes, G Higa
Analytical Oncology 9, 25 - 32

Nano-Adjuvants
B Misra, KA Hughes, S Bobbala
Nanomedicines for the Prevention and Treatment of Infectious Diseases 56 …

Oleic Acid Integrated Acetalated Dextran Nanoparticles for Enhanced Chemotherapeutic Delivery to the Bone Marrow
KA Hughes, WH Pentz, B Misra, M Surface, WJ Geldenhuys, S Hussain, ...
ACS Applied Materials & Interfaces 17 (45), 61799

Orthopedic applications of silver and silver nanoparticles
J Kang, K Hughes, M Xing, B Li
Orthopedic Biomaterials: Advances and Applications, 63-83

Osteoarthritis in older adults: nonsteroidal anti-inflammatory drugs versus opioids
C Banks, K Hughes, C Simpkins, DP Elliott
The Senior Care Pharmacist 34 (10), 674-677

Silver nanoparticles present high intracellular and extracellular killing against Staphylococcus aureus
J Kang, MJ Dietz, K Hughes, M Xing, B Li
Journal of Antimicrobial Chemotherapy 74 (6), 1578-1585

TLR7-adjuvanted ionizable lipid nanoparticles for mRNA vaccine delivery
B Misra, KA Hughes, WH Pentz, M Surface, WJ Geldenhuys, S Bobbala
The AAPS Journal 27 (4), 80

Use of stimulatory responsive soft nanoparticles for intracellular drug delivery
KA Hughes, B Misra, M Maghareh, S Bobbala
Nano Research 16 (5), 6974-6990

Dr. Krystal Ann Hughes is an Assistant Professor in the West Virginia University School of Pharmacy and the WVU School of Medicine. She also serves as the Director of Interdisciplinary Pharmacology Education, a newly created role with the goal of enhancing students’ understanding of pharmacology across professional disciplines. She joined the faculty at WVU in August 2026. As a WVU alumna, she earned her MS in Clinical and Translational Science and her PharmD in 2021. She earned her PhD in Pharmaceutical and Pharmacological Sciences in 2025.