Hedjazi Moghari

Mehdi Hedjazi Moghari, PhD

Associate Professor, Division of Pediatric Cardiology, Co-Director of Research-Heart Institute

Contact

Phone
304-293-2416
Fax
304-293-1409
Address
PO Box 9214
Department of Pediatrics
Division of Pediatric Cardiology
Morgantown, WV 26506-9214
Additions & Corrections?

Positions

Associate Professor, Division of Pediatric Cardiology, Co-Director of Research-Heart Institute

Organization:
School of Medicine
Department:
Pediatrics
Classification:
Faculty

Education

  • PhD, Queens University, Canada, 2008

Publications

 
  • Pace DF, Contreras H, Ghelani S, Rahaman I, Zhang Y, Gao P, Jubair MI, Yeh T, Golland P, Geva T, Ghelani S, Powell AJ, Romanowicz J, Moghari MH. HVSMR-2.0: A 3D cardiovascular MR dataset for whole-heart segmentation in congenital heart disease. Nature Sci Data. 2024; 11(1): 721.
  • Laudenschlager S, Schofield S, Drysdale N, Stone M, Romanowicz J, Frank B, DiMaria M, Kheyfets VO, Moghari MH. Estimation of pulmonary vascular resistance for Glenn physiology. PLoS One 2024 Jul 26;19(7).
     
  • Tayebi Arasteh S, Romanowicz J, Pace DF, Golland P, Powell AJ, Maier AK, Truhn D, Brosch T, Weese J, Lotfinia M, van der Geest RJ and Moghari MH. Automated segmentation of 3D cine cardiovascular magnetic resonance imaging. Front. Cardiovasc. Med 2023; 10:1167500.
     
  • Gonzalez de Alba C, Moghari MH, Browne LP, Friesen RM, Fonseca B and Malone LJ. Feasibility of gray-blood late gadolinium enhancement evaluation in young patients with congenital and acquired heart disease. Front. Cardiovasc. Med. 2023; 10:1269412.
     
  • Sun X, Cheng L, Plein S, Garg P, Moghari MH, van der Geest RJ. Deep learning-based prediction of intra-cardiac blood flow in long-axis cine magnetic resonance imaging. Int J Cardiovasc Imaging 2023; 39:1045–1053.
     
  • Braunstorfer L, Romanowicz J, Powell AJ, Pattee J, Browne LP, van der Geest RJ, Moghari MH. Non-contrast free-breathing whole-heart 3D cine cardiovascular magnetic resonance with a novel 3D radial leaf trajectory. Magn Reson Imaging 2022; 94:64-72.
     
  • Javadi E, Laudenschlager S, Kheyfets V, Di Maria M, Stone M, Jamali S, Powell AJ, Moghari MH. Predicting hemodynamic performance of Fontan operation for Glenn physiology using computational fluid dynamics: Ten patient-specific cases. J Clin Images Med Case Rep. 2022; 3(6): 1916.
     
  • Pace DF, Dalca AV, Brosch T, Geva T, Powell AJ, Weese J, Moghari MH, Golland P. Learned iterative segmentation of highly variable anatomy from limited data: Applications to whole heart segmentation for congenital heart disease. Med Image Anal 2022 Aug;80:102469.
     
  • Sohani M, van der Geest R, Maier A, Powell AJ, Moghari MH. Improved cardiac T1 mapping accuracy and precision with a new hybrid MOLLI and SASHA technique: MOSHA. Magn Reson Imaging 2022;89:33-41.
     
  • Fok WYR, Chan YCI, Romanowicz J, Jang J, Powell AJ, Moghari MH. Accelerated free-breathing 3D whole-heart magnetic resonance angiography with a radial phyllotaxis trajectory, compressed sensing, and curvelet transform. Magn Reson Imaging 2021;83:57-67.
     
  • Kleist HV, Buehrer M, Kozerke S, Saengsin K, Harrington JK, Powell AJ, Moghari MH. Cardiac self-gating using blind source separation for 2D cine cardiovascular magnetic resonance imaging. Magn Reson Imaging 2021;81:42-52.
     
  • Moghari MH, van der Geest RJ, Brighenti M, Powell AJ. Cardiac magnetic resonance using fused 3D cine and 4D flow sequences: Validation of ventricular and blood flow measurements. Magn Reson Imaging 2020;74:203-212.
     
  • Moghari MH, Barthur A, Amaral ME, Geva T, Powell AJ. Free-breathing whole-heart 3D cine magnetic resonance imaging with prospective respiratory motion compensation. Magn Reson Med 2018;80:181-189.
     
  • Moghari MH, Uecker M, Roujol S, Sabbagh M, Geva T, Powell AJ. Accelerated whole-heart MR angiography using a variable-density poisson-disc undersampling pattern and compressed sensing reconstruction. Magn Reson Med 2018;79:761-769.
     
  • Moghari MH, Geva T, Powell AJ. Prospective heart tracking for whole-heart magnetic resonance angiography. Magn Reson Med 2017;77:759-765.
     
  • Moghari MH, Annese D, Geva T, Powell AJ. Three-dimensional heart locator and compressed sensing for whole-heart magnetic resonance angiography. Magn Reson Med 2016;75:2086-2093.
     
  • Moghari MH, Komarlu R, Annese D, Geva T, Powell AJ. Free-breathing steady-state free precession cine cardiac magnetic resonance with respiratory navigator gating. Magn Reson Med 2015;73:1555-1561.
     
  • Moghari MH, Roujol S, Henningsson M, Kissinger KV, Annese D, Nezafat R, Manning WJ, Geva T, Powell AJ. Three-dimensional heart locator (3D-LOC) for whole-heart coronary magnetic resonance angiography. Magn Reson Med 2014;71:2118-2126.
     
  • Roujol S, Basha TA, Tan AY, Khanna V, Chan RH, Moghari MH, Rayatzadeh H, Shaw JL, Josephson ME, Nezafat R. Improved multi-modality data fusion of late gadolinium enhancement MRI to left ventricular voltage maps in ventricular tachycardia ablation. IEEE Trans Biomed Engineering 2013;60:1308-1317.
     
  • Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows-gated late gadolinium enhancement of the left atrium. J Magn Reson Imaging 2013;38:1210-1214.
     
  • Moghari MH, Roujol S, Chan RH, Hong SN, Bello N, Henningsson M, Ngo LH, Goddu B, Goepfert L, Kissinger KV, Manning WJ, Nezafat R. Free-breathing 3D cardiac MRI using iterative image-based respiratory motion correction. Magn Reson Med 2013; 70:1005-1015.
     
  • Moghari MH, Chan RH, Hong SN, Shaw JL, Goepfert L, Kissinger KV, Goddu B, Josephson ME, Manning WJ, Nezafat R. Free-breathing cardiac MR with a fixed navigator efficiency using adaptive gating window size. Magn Reson Med 2012;86:1866-1875.
     
  • Moghari MH, Hu P, Kissinger KV, Goddu B, Goepfert L, Ngo L, Manning WJ, Nezafat R. Subject-specific estimation of respiratory navigator tracking factor for free-breathing cardiovascular MR. Magn Reson Med 2012;67:1665-1672.
     
  • Moghari MH, Akçakaya M, O’Connor AC, Basha TA, Casanova M, Stanton D, Goepfert L, Kissinger KV, Goddu B, Chuang ML, Tarokh V, Manning WJ, Nezafat R. Compressed-sensing motion compensation (CosMo): A joint prospective-retrospective respiratory navigator for coronary MRI. Magn Reson Med 2011;66:1674-1681.
     
  • Hu P, Hong SN, Moghari MH, Goddu B, Goepfert L, Hauser TH, Manning WJ, Nezafat R. Motion correction using coil arrays (MOCCA) for free-breathing cardiac cine MRI. Magn Reson Med 2011;66:467-475.
     
  • Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free-breathing left atrium late gadolinium enhancement. Magn Reson Med 2011;66:180-186.
     
  • Akçakaya M, Nam S, Hu P, Moghari MH, Ngo LH, Tarokh V, Manning WJ, Nezafat R. Compressed sensing with wavelet domain dependencies for coronary MRI: A retrospective study. IEEE Trans Med Imaging 2011;30:1090-1099.
     
  • Moghari MH, Abolmaesumi P. Understanding the effect of bias in fiducial localization error on rigid-body point-based registration. IEEE Trans Med Imaging 2010;29:1730-1738.
     
  • Ma B, Moghari MH, Abolmaesumi P, Ellis R. Estimation of optimum fiducial target registration error in the presence of anisotropic noise. IEEE Trans Med Imaging 2010;29:708-723.
     
  • Moghari MH, Abolmaesumi P. Distribution of fiducial registration error in rigid-body point-based registration. IEEE Trans Med Imaging 2009;28:1791-1801.
     
  • Moghari MH, Abolmaesumi P. Distribution of target registration error for anisotropic and inhomogeneous fiducial localization error. IEEE Trans Med Imaging 2009;28:799-813.
     
  • Moghari MH, Abolmaesumi P. Point-based rigid-body registration using an unscented Kalman filter. IEEE Trans Med Imaging 2007;26:1708-1728.

Additional Info

Dr. Mehdi Hedjazi Moghari was an Instructor of Pediatrics, Division of Cardiology at Harvard Medical School from 2012 to 2016; Assistant Professor of Pediatrics, Division of Cardiology at Harvard Medical School from 2016-2021, and a Visiting Associate Professor of Radiology at the University of Colorado from 2021-2024. 

Research Program

Pediatric Cardiology

Research Interests

Research interests:
My research focuses on advancing the care of children and fetuses with congenital heart disease (CHD). I am dedicated to developing innovative approaches that not only improve the quality of life for these young patients but also improve the accuracy of prenatal detection of CHD. By integrating cutting-edge imaging techniques and fostering early diagnosis, I aim to transform outcomes and provide a brighter, healthier future for children affected by this challenging condition.
Additionally, I am integrating artificial intelligence into healthcare to further elevate precision and accuracy in diagnosis and treatment. Through these advancements, my goal is to drive forward impactful changes that will fundamentally improve patient care and outcomes in the field of congenital heart disease.

Grants and Research

Research Topics:
1. Developing a Digital Twin of Pediatric Hearts for Enhanced Surgical Simulation and Personalized Planning in Congenital Heart Disease
2. Advanced Simulation of Surgical Interventions for Severe Congenital Heart Disease Using Computational Fluid Dynamics
3. Longitudinal Analysis of Blood Flow Dynamics, Hemodynamics, and Morphological Changes in Pediatric Patients with Single Ventricle Physiology
4. Identifying Novel Biomarkers to Predict Outcomes and Optimize Fontan Surgery for Pediatric Single Ventricle Patients
5. Integrative Monitoring of Neurocardiac and Placental Development in Fetuses with Congenital Heart Disease
6. Innovative In Utero Interventions for Fetuses Diagnosed with Congenital Heart Disease: Techniques and Outcomes
7. Innovative Development of Artificial Intelligence Models Integrating Multidimensional and Multimodal Patient Data for Enhanced Precision and Accuracy
 
 

Patient Care Information

Medical Specialties

  • Pediatric Cardiology
  • Pediatrics

Special Training

  • Fellowship, Postdoctoral Research Fellow, Department of Medicine
    Harvard Medical School, MA, 2012