Christopher McCartney, MD

Vice Chair of Research, Professor of Endocrinology

Organization:

West Virginia University School of Medicine

Department:

Medicine

Classification:

Faculty

• MD, University of Mississippi School of Medicine, 1996
• MS, University of Virginia School of Medicine, 2007

Latronico AC, Roberts SA, Alonzo M, Argente J, Canton APM, Carel J-C, Cassorla F, Charmandari E, Eugster EA, Grandone A, Greenspan LC, Hawse EC, Juul A, Kaplowitz PB, Murad MH, Street ME, Walker V, McCartney CR. Central precocious puberty: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2026 [in press]

McCartney CR, Pannone AF, Kim SH, Gurka MJ, DeBoer MD, Burt Solorzano CM. Free testosterone independently predicts metabolic syndrome severity in U.S. adolescent girls aged 12–19 years. J Endocr Soc 2026 Mar 11;10(4):bvag055

Houghton MA‡, McCartney CR‡, Kim SH, Patrie JT, Marshall JC, Burt Solorzano CM. Evidence for functional ovarian hyperandrogenism in early pubertal, but not late pubertal, girls with overweight. ‡ = contributed equally. J Endocr Soc 2025 Oct 1;9(12):bvaf154
Kim SH, Pannone AF, DeBoer MD, McCartney CR‡, Burt Solorzano CM‡. Obesity is associated with hyperandrogenemia in a nationally representative sample of US girls aged 6 to 18 years. ‡ = contributed equally. J Clin Endocrinol Metab 2025;110:e1289–e1290

McCartney CR, McDonnell ME, Corrigan MD, Lash RW. Vitamin D insufficiency and epistemic humility: an Endocrine Society guideline communication. J Clin Endocrinol Metab 2024;109:1948–1954

Ospina NS, Diaz-Thomas A, McDonnell ME, Demay MB, Pittas AG, York E, Corrigan MD, Lash RW, Brito JP, Murad MH, McCartney CR. Navigating complexities: vitamin D, skin pigmentation, and race. J Clin Endocrinol Metab 2024; 109: 1955–1960

Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh J, McCartney CR. Vitamin D for the prevention of disease: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2024;109:1907–1947

[Textbook chapter] McCartney CR, Marshall JC. Neuroendocrinology of Reproduction. (Chapter 1) In Strauss JF, Barbieri R, Dokras A, Williams CJ, Williams Z (eds), Yen & Jaffe's Reproductive Endocrinology: Physiology, Pathophysiology, and Clinical Management, 9th edition, Elsevier, 2023

McCartney CR, Corrigan MD, Drake MT, El-Hajj Fuleihan G, Korytkowski MT, Lash RW, Lieb DC, McCall AL, Muniyappa R, Piggott T, Santesso N, Schünemann HJ, Wiercioch W, McDonnell ME, Murad MH. Enhancing the trustworthiness of Endocrine Society’s clinical practice guidelines. J Clin Endocrinol Metab 2022;107(8):2129–2138

Kim SH, Lundgren JA, Patrie JT, Burt Solorzano CM, McCartney CR. Acute progesterone feedback on gonadotropin secretion is not demonstrably altered in estradiol-pretreated women with polycystic ovary syndrome. Physiol Rep 2022;10:e15233

McCartney CR, Campbell RE, Marshall JC, Moenter SM. The role of gonadotropin-releasing hormone neurons in polycystic ovary syndrome. J Neuroendocrinol 2022;00:e13093

[Textbook chapter] McCartney CR. “The Menstrual Cycle and Disorders of Ovulation,” DeGroot’s Endocrinology, 8th edition (Eds., Robertson RP, Giudice LC, Grossman A, Hammer G, Jensen MD, Kahaly GJ, Swerdloff RS, Thakkeret R), Elsevier, 2022 [2026 update in review]

[Textbook chapter] Baker FC, McCartney CR. “Menstrual Cycle, Sleep, and Circadian Rhythms,” Women and Sleep Section, Principles and Practice of Sleep Medicine, 7th edition (Eds., Kryger, Roth, Dement), Elsevier, Philadelphia, PA, 2022 [2026 update in press]

Burt Solorzano C, McCartney CR. Polycystic ovary syndrome: Ontogeny in adolescence. Endocrinol Metab Clin North Am 2021;50:25–42

McCartney CR, Campbell RE. Abnormal GnRH pulsatility in polycystic ovary syndrome: recent insights. Current Opinion in Endocrine and Metabolic Research 2020;12:78–84

McCartney CR, Gianoukakis AG, Gopalakrishnan G, McGill JB, Roach PJ, Siraj ES, True MW. Voluntary adoption of an All In Match Policy in the Medical Specialties Matching Program: advantages and disadvantages. J Grad Med Educ 2019;11(4):378–381

McCartney CR, Rosen CJ. Conflict of interest in clinical practice guidelines: accelerating an evolution. An Endocrine Society consensus statement. J Clin Endocrinol Metab 2018;103:4339–4342

McCartney CR, Burt Solorzano CM, Marshall JC, Haisenleder DJ. Estimating testosterone concentrations in adolescent girls: comparison of two direct immunoassays to liquid chromatography-tandem mass spectrometry. Steroids 2018;140:62–69

Burt Solorzano CM, Knudsen KL, Anderson AD, Hutchens EG, Collins JS, Patrie JT, Marshall JC, McCartney CR. Insulin resistance, hyperinsulinemia, and LH: relative roles in peripubertal obesity-associated hyperandrogenemia. J Clin Endocrinol Metab 2018;103:2571–2582

Kim SH, Burt Solorzano CM, McCartney CR. Progesterone administration does not acutely alter LH pulse secretion in the mid-follicular phase in women. Physiol Rep 2018;6(7).pii:e13680

Lu C, Hutchens EG, Farhi LS, Bonner HG, Suratt PM, McCartney CR. Influence of sleep stage on sleep-associated LH pulse initiation in normal mid- to late follicular phase women and in women with polycystic ovary syndrome. Neuroendocrinology 2018;107:60–72

Kim SH, Lundgren JA, Bhabhra R, Collins JS, Patrie JT, Burt Solorzano CM, Marshall JC, McCartney CR. Progesterone-mediated inhibition of the GnRH pulse generator: differential sensitivity as a function of sleep status. J Clin Endocrinol Metab 2018;103:1112–1121

Hutchens EG, Ramsey KA, Howard LC, Abshire MY, Patrie JT, McCartney CR. Progesterone has rapid positive feedback actions on LH release but fails to reduce LH pulse frequency within 12 hours in estradiol-pretreated women. Physiol Rep 2016 Aug;4(16).pii:e12891

McCartney CR, Marshall JC. CLINICAL PRACTICE. Polycystic ovary syndrome. N Engl J Med 2016;375:54–64

1994 Induction into Alpha Omega Alpha, University of Mississippi SOM

2009 Award for Excellence in Research, UVA DOM

2010 Mulholland Award for Teaching Excellence in Foundations of Medicine, UVA SOM

2011 Outstanding Teaching Award, UVA DOM

2011 Dean’s Excellence in Teaching Award, UVA SOM

2011 Induction into the Dean’s Academy of Distinguished Educators, UVA SOM

2012 Mulholland Award for Teaching Excellence in Foundations of Medicine, UVA SOM

2012 Faculty Recognition Award for Outstanding Educator, UVA DOM

2012 Dean’s Faculty Excellence in Research Award, UVA SOM

2017 Award for Excellence in Mentoring, UVA DOM

Selected National Service:

• 2026: Ad hoc reviewer, NIH/NICHD Special Emphasis Panel to Review Mentored Research Scientist Development applications
• 2026–present: Co-Director, Residents Research Academy, West Virginia Clinical and Translational Science Institute (WVCTSI)
• 2025–present: Program Lead for the Endocrine Society-sponsored Medical School Engagement Program (MSEP) for West Virginia University School of Medicine 
• 2025–present: Co-Director, Fellows Research Academy, West Virginia Clinical and Translational Science Institute (WVCTSI)
• 2023–2025: Ethics and Professionalism Committee, Endocrine Society (Vice Chair 2023–2024)
• 2023–2024: Associate Editor (female reproduction) for the Journal of Clinical Endocrinology and Metabolism
• 2022–2023: Clinical Science Chair, 2023 Annual Meeting Steering Committee, Endocrine Society
• 2021–present: Endocrine Society Guideline Methodologist
• 2021–2022: Editorial Board, Journal of Clinical Endocrinology and Metabolism (JCEM)
• 2020–2023: Standing member, NIH/NICHD Reproduction, Andrology, and Gynecology Study Section
• 2020–2023: Member of Endocrine Society Conflict of Interest (COI) Policy Review Working Group (2020); and Chair of Endocrine Society COI Advisory Group (2021–2023)
• 2016–2021: Endocrine Society Clinical Guidelines Committee (Member 2016–2018, Chair 2018–2021)
• 2014–2021: Council member, Association of Program Directors in Endocrinology, Diabetes, and Metabolism (APDEM), including terms as Secretary-Treasurer (2016–2017), President-Elect (2017–2018), President (2018–2020), and Immediate Past President (2020–2021)
• 2012–2015: Member, Annual Meeting Steering Committee, Endocrine Society

Dr. McCartney completed medical school and internal medicine residency at the University of Mississippi (1992–1999), thereafter completing a fellowship in endocrinology and metabolism at the University of Virginia (UVA; 1999–2002). He was a faculty member at UVA from 2002 to 2023, but in early 2024, Dr. McCartney came to WVU to serve as Vice Chair for Research in the Department of Medicine. Dr. McCartney's clinical (patient-oriented) research has largely focused on reproductive neuroendocrinology and the pathophysiology of polycystic ovary syndrome (PCOS), and he has been the recipient of an NIH K23 career-development award, two NIH R01 grants, and an R01-equivalent grant (NIH P50 project). Dr. McCartney has been heavily involved with the Endocrine Society: He has chaired the Clinical Guidelines Committee (2018–2021) and the Conflict of Interest Advisory Group (2021–2023); he was Clinical Science Chair for the 2023 Annual Meeting Steering Committee; he was an Associate Editor for the Journal of Clinical Endocrinology and Metabolism (2023–2024); and he will be a member of the Society’s Board of Directors (2026–2029). Dr. McCartney has also had a long-standing interest in graduate medical education and mentorship: He served as endocrinology fellowship program director at UVA (2011–2020); he was President of the Association of Program Directors in Endocrinology and Metabolism from 2018 to 2020; and he currently serves as Co-Director for West Virginia Clinical and Translational Science Institute’s Fellows Research Academy and Resident Research Academy.

Medical Specialties

• Internal Medicine

Special Training

• Fellowship, Research Fellowship
  Center for Research in Reproduction, University of Virginia School of Medicine, 2003
• Fellowship, Endocrinology and Metabolism Fellowship
  University of Virginia School of Medicine, 2002
• Residency, Internal Medicine Residency
  University of Mississippi School of Medicine, Jackson, MS, 1999