Christopher McCartney, MD

Vice Chair of Research, Professor of Endocrinology

Organization:

West Virginia University School of Medicine

Department:

Medicine

Classification:

Faculty

• MD, University of Mississippi School of Medicine, 1996
• MS, University of Virginia School of Medicine, 2007

Sarpong KAN*, Kim SH, McCartney CR, Wiencek JR, Bazydlo LAL. Spironolactone metabolite causes falsely increased progesterone in the Abbott Architect immunoassay. Clin Biochem 2024 Apr:126:110747

Demay MB*, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M, Lips P, Mitchell DM, Murad MH, Powers S, Rao SD, Scragg R, Tayek JA, Valent AM, Walsh J, McCartney CR. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2024; 109: 1907–1947

Ospina NS, Diaz-Thomas A, McDonnell ME, Demay MB, Pittas AG, York E, Corrigan MD, Lash RW, Brito JP, Murad MH, McCartney CR*. Navigating Complexities: Vitamin D, Skin Pigmentation, and Race. J Clin Endocrinol Metab 2024; 109: 1955–1960

McCartney CR*, McDonnell ME, Corrigan MD, Lash RW. Vitamin D Insufficiency and Epistemic Humility: An Endocrine Society Guideline Communication. J Clin Endocrinol Metab 2024; 109: 1948–1954

Kim SH, Pannone AF, DeBoer MD, McCartney CR‡, Burt Solorzano CM‡. Obesity is associated with hyperandrogenemia in a nationally representative sample of US girls aged 6 to 18 years. ‡ = contributed equally. J Clin Endocrinol Metab 2024 2024 Sep 23:dgae645. Online ahead of print. [PMID 39311388; DOI 10.1210/clinem/dgae645] 

McCartney CR, Marshall JC*. CLINICAL PRACTICE. Polycystic ovary syndrome. N Engl J Med 2016;375:54–64.

Hutchens EG, Ramsey KA, Howard LC, Abshire MY, Patrie JT, McCartney CR*. Progesterone has rapid positive feedback actions on LH release but fails to reduce LH pulse frequency within 12 hours in estradiol-pretreated women. Physiol Rep 2016 Aug;4(16).pii:e12891.

Tannus S*, Burke Y, McCartney CR, Kol S. GnRH-agonist triggering for final oocyte maturation in GnRH-antagonist IVF cycles induces decreased LH pulse rate and amplitude in early luteal phase: a possible luteolysis mechanism. Gynecol Endocrinol 2017;33:741–745.

Goldman MD*, Koenig S, Engel C, McCartney CR, Sohn M-W. Glucocorticoid-associated blood glucose response and multiple sclerosis relapse recovery. Neurol Neuroimmunol Neuroinflamm 2017 Jul 18;4(5):e378.

Lundgren JA*, Kim SH, Burt Solorzano CM, McCartney CR, Marshall JC. Progesterone suppression of LH pulse frequency in adolescent girls with hyperandrogenism: effects of metformin. J Clin Endocrinol Metab 2018;103:263–270.

Kim SH, Lundgren JA, Bhabhra R, Collins JS, Patrie JT, Burt Solorzano CM, Marshall JC, McCartney CR*. Progesterone-mediated inhibition of the GnRH pulse generator: differential sensitivity as a function of sleep status. J Clin Endocrinol Metab 2018;103:1112–1121.

Burt Solorzano CM*, Helm KD, Patrie JT, Shayya RF, Cook-Andersen HL, Chang RJ, McCartney CR, Marshall JC. Increased adrenal androgens in overweight peri-pubertal girls. J Endocr Soc 2017;1:538–552.

Lu C, Hutchens EG, Farhi LS, Bonner HG, Suratt PM, McCartney CR*. Influence of sleep stage on sleep-associated LH pulse initiation in normal mid- to late follicular phase women and in women with polycystic ovary syndrome. Neuroendocrinology 2018;107:60–72.

Kim SH, Burt Solorzano CM, McCartney CR*. Progesterone administration does not acutely alter LH pulse secretion in the mid-follicular phase in women. Physiol Rep 2018;6(7).pii:e13680.

Burt Solorzano CM, Knudsen KL, Anderson AD, Hutchens EG, Collins JS, Patrie JT, Marshall JC, McCartney CR*. Insulin resistance, hyperinsulinemia, and LH: relative roles in peripubertal obesity-associated hyperandrogenemia. J Clin Endocrinol Metab 2018;103:2571–2582.

McCartney CR*, Burt Solorzano CM, Marshall JC, Haisenleder DJ. Estimating testosterone concentrations in adolescent girls: comparison of two direct immunoassays to liquid chromatography-tandem mass spectrometry. Steroids 2018;140:62–69.

McCartney CR*, Rosen CJ. Conflict of interest in clinical practice guidelines: accelerating an evolution. An Endocrine Society consensus statement. J Clin Endocrinol Metab 2018;103:4339–4342.

Wiencek JR*, McCartney CR, Chang AY, Straseski JA, Auchus RJ, Woodworth A. Challenges in the assessment and diagnosis of polycystic ovary syndrome. Question and Answer Commissioned Article. Clin Chem 2019;65:370–377.

McCartney CR*, Gianoukakis AG, Gopalakrishnan G, McGill JB, Roach PJ, Siraj ES, True MW. Voluntary adoption of an All In Match Policy in the Medical Specialties Matching Program: advantages and disadvantages. J Grad Med Educ 2019;11(4):378–381.

McCartney CR*, Campbell RE. Abnormal GnRH pulsatility in polycystic ovary syndrome: recent insights. Current Opinion in Endocrine and Metabolic Research 2020;12:78–84.

Burt Solorzano C, McCartney CR*. Polycystic ovary syndrome: Ontogeny in adolescence. Endocrinol Metab Clin North Am 2021;50:25–42.

McCartney CR*. Higher-level modulation of GnRH secretion: progress toward next-generation reproductive treatments? J Clin Endocrinol Metab 2021;106:e3272-e3274.

Elghawy O, Hafey AC, McCartney CR, Steinman JR*. Successful treatment of myxedema coma using levothyroxine and liothyronine in the setting of adrenal crisis and severe cardiogenic shock in a patient with apparent primary empty sella. J Clin Transl Endocrinol Case Rep 2021;22:100095.

Steinman JR*, Thomas MH, McCartney CR, Padia SH. A novel pathogenic variant in MAX-associated pheochromocytoma. J Clin Transl Endocrinol Case Rep 2021;22:100101.

Esquivel-Zuniga R, Kirschner CK, McCartney CR, Burt Solorzano CM*. Non-PCOS hyperandrogenic disorders in adolescents. Semin Reprod Med 2022;40:42–52.

McCartney CR*, Campbell RE, Marshall JC, Moenter SM. The role of gonadotropin-releasing hormone neurons in polycystic ovary syndrome. J Neuroendocrinol 2022;00:e13093.

Kim SH*, Lundgren JA, Patrie JT, Burt Solorzano CM, McCartney CR. Acute progesterone feedback on gonadotropin secretion is not demonstrably altered in estradiol-pretreated women with polycystic ovary syndrome. Physiol Rep 2022;10:e15233.

McCartney CR*, Corrigan MD, Drake MT, El-Hajj Fuleihan G, Korytkowski MT, Lash RW, Lieb DC, McCall AL, Muniyappa R, Piggott T, Santesso N, Schünemann HJ, Wiercioch W, McDonnell ME, Murad MH. Enhancing the trustworthiness of Endocrine Society’s clinical practice guidelines. J Clin Endocrinol Metab 2022;107(8):2129–2138.

1994 Induction into Alpha Omega Alpha, University of Mississippi SOM

2009 Award for Excellence in Research, UVA DOM

2010 Mulholland Award for Teaching Excellence in Foundations of Medicine, UVA SOM

2011 Outstanding Teaching Award, UVA DOM

2011 Dean’s Excellence in Teaching Award, UVA SOM

2011 Induction into the Dean’s Academy of Distinguished Educators, UVA SOM

2012 Mulholland Award for Teaching Excellence in Foundations of Medicine, UVA SOM

2012 Faculty Recognition Award for Outstanding Educator, UVA DOM

2012 Dean’s Faculty Excellence in Research Award, UVA SOM

2017 Award for Excellence in Mentoring, UVA DOM

Selected National Service:

2012–2015 - Member, Annual Meeting Steering Committee, Endocrine Society

2014–2021 - Council member, Association of Program Directors in Endocrinology, Diabetes, and Metabolism (APDEM), including terms as Secretary-Treasurer (2016–2017), President-Elect (2017–2018), President (2018–2020), and Immediate Past President (2020–2021)

2016–2021 - Endocrine Society Clinical Guidelines Committee (Member 2016–2018, Chair 2018–2021)

2020–2023 - Member of Endocrine Society Conflict of Interest (COI) Policy Review Working Group (2020); and Chair of Endocrine Society COI Advisory Group (2021–2023)

2020–2021 - Question writer/reviewer for Female Reproductive section of American Association of Clinical Endocrinology (AACE) Self-Assessment Program

2020–2023 - Standing member, NIH/NICHD Reproduction, Andrology, and Gynecology Study Section

2021–2022 - Editorial Board, Journal of Clinical Endocrinology and Metabolism (JCEM)

2021–present - Endocrine Society guideline methodologist

2021–2024 - Member of guideline development panel for Endocrine Society’s clinical practice guideline related to vitamin D deficiency

2022–2023 - Clinical Science Chair, 2023 Annual Meeting Steering Committee, Endocrine Society

2023–2024 - Associate Editor (female reproduction) for the Journal of Clinical Endocrinology and Metabolism

2023–present – Ethics and Professionalism Committee, Endocrine Society

2024-present - Member of guideline development panel for Endocrine Society’s clinical practice guideline related to central precocious puberty

Medical Specialties

• Internal Medicine

Special Training

• Fellowship, Research Fellowship
  Center for Research in Reproduction, University of Virginia School of Medicine, 2003
• Fellowship, Endocrinology and Metabolism Fellowship
  University of Virginia School of Medicine, 2002
• Residency, Internal Medicine Residency
  University of Mississippi School of Medicine, Jackson, MS, 1999