Contact
Positions
Assistant Professor
- Organization:
- West Virginia University School of Medicine
- Department:
- Microbiology, Immunology & Cell Biology
- Classification:
- Faculty
Member
- Organization:
- West Virginia University WVU Cancer Institute
- Department:
- WVU Cancer Institute Research Programs
- Classification:
- Faculty
Education
- PhD, University of Toronto, 2013
Publications
Recent Publications:
- Liu TW, Gammon ST, Yang P, Ma W, Wang J, Piwnica-Worms D. Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma. Journal for ImmunoTherapy of Cancer. 2023. 11:e005837. PMCID: PMC9944647
- Liu TW, Gammon ST, Yang P, Fuentes D, Piwnica-Worms D. HOCl is a Paracrine Effector Linking Myeloid Cells to NF-κB Signaling in melanoma by Trans-inhibition of IKK. Science Signaling. 2021. 14 (677). PMID: 33824181
- Liu TW, Gammon ST, Piwnica-Worms D. Multi-dimensional intravital microscopy of signaling dynamics in real-time during tumor-immune interactions. Cells. 2021. 10(3). 499. PMCID: PMC7996937
- Liu TW, Gammon ST, Fuentes D, Piwnica-Worms D. Multi-dimensional intravital macro-imaging of signaling dynamics in real-time during tumor-immune interactions. Cells. 2021. 10 (3), 489. PMCID: PMC7996138
- Liu TW, Akens MK, Chen J, Wilson BC, Zheng G. Matrix metalloproteinase-based photodynamic molecular beacons for targeted destruction of bone metastases in vivo. Photochem & Photobiol Sci. 2016; 15(3):375-381
- Liu TW, Chen J, Burgess L, Wilson BC, Zheng G, Zhang L, Liu WK, Ha Bae-Yuen. Activation Kinetics of Zipper Molecular Beacons. J. Phys. Chem. B. 2015;119(1):44-53
- Liu TW, Huynh E, MacDonald TD, Zheng G. Porphyrins for Imaging, Photodynamic Therapy a d Photothermal Therapy. In: Cancer Theranostics. Ed(s): Chen X, Wong S. Academmic Press. 2014; 229-254.
- Liu TW†, Stewart JM†, MacDonald TD, Chen J, Clarke B, Shi J, Wilson BC, Neel BG, Zheng G. Biologically-Targeted Detection of Primary and Micro-Metastatic Ovarian Cancer. Theranostics. 2013; 3(6):420-427.
- Liu TW†, MacDonald TD†, Jin CS, Gold JM, Bristow RG, Wilson BC, Zheng G. Inherently Multimodal Nanoparticle-Driven Tracking and Real-Time Delineation of Orthotopic Prostate Tumors and Micrometastases. ACS Nano. 2013;7(5):4221-32.
- Liu TW†, Macdonald TD†, Shi J, Wilson BC, Zheng G. Intrinsically copper-64-labeled organic nanoparticles as radiotracers. Angew Chem Int Ed Engl. 2012;51:13128-31.
(†authors contributed equally to the work)
Research Interests
With the paradoxical dual role that the immune microenvironment plays during cancer progression, it is essential to understand the specific mechanisms controlled by immune cell infiltrates during tumor development and the complex interaction networks between immune and tumor cells to improve mechanistic insight, enhance disease detection and improve therapeutic response. Our research focuses on strategies to understand interaction networks between tumor and immune cells.