Subit Barua, PhD, DABMGG, FACMG

Assistant Professor of Pathology, Director of Molecular Pathology

Organization:

West Virginia University School of Medicine

Department:

Pathology, Anatomy and Laboratory Medicine

Classification:

Faculty

• PhD, St. John's University, NY, 2012
• LGG, Columbia University Irving Medical Center, NY, 2021

Publications:

Barua , Jobanputra et al. Expanding the phenotype of ATP6AP1 deficiency. Cold Spring Harb Mol Case Stud (2022); PMID:35732497

Ganapathi, Barua, Jobanputra et al. Clinical exome sequencing for inherited retinal degenerations at a tertiary care center. Sci Rep. (2022); PMID: 35672425

Barua, Fernandes et al. Quality metrics for enhanced performance of an NGS panel using single-vial amplification technology  J Clin Pathol (2022); PMID: 36376073

Sasi, Barua, Perrotta et al. A treatment-refractory aggressive MDS-MLD with multiple highly complex chromosome 5 intrachromosomal rearrangements: a case report. Mol Cytogenet (2022); PMID:36474285

Barua S, Levy B, Liao J, et al: 3q27.1 microdeletion causes a clinically recognizable syndrome characterized by severe prenatal and postnatal growth restriction and neurodevelopmental abnormalities Molecular Cytogenetics, (2022)., PMID: 35241116

Kushary,S, Politi, A, Barua S, K A Yeboa et al: ZTTK syndrome: Clinical and molecular findings of 15 cases and a review of the literature Am J Med Genet A. 2021 PMID: 34331327.

Lippa N, Barua S, Bain J et al: A novel de novo KDM5C variant in a female with global developmental delay and ataxia: a case report BMC Neurol. 2021 PMID: 34530748

Barua S, Fernandes H, et al: Key Considerations for Comprehensive Validation of a RNA Fusion NGS Panel. Pract Lab Med.(2020), PMID: 32613069

Pagan C, Barua S, Fernandes H, et al: Targeting SLMAP-ALK—a novel gene fusion in lung adenocarcinoma Cold Spring Harb Mol Case Stud. 2019, PMID: 31160357

Barua S et al: DNA methylation analysis at single base  resolution revealed gestational folic acid supplementation alters methylation and expression of genes in cerebellum of offspring  Frontiers in Neuroscience (2016), PMID: 27199632

Barua S et al: High gestational folic acid supplementation alters expression of imprinted and candidate autism susceptibiliyt gene in a gender specific manner J Mol Neurosci. (2015), PMID: 26547318

Barua S and Junaid MA: Life style, pregnancy and epigenetic effects. Epigenomics (2015), PMID: 25687469

Barua S et al (2015): Microarray analysis revealed higher gestational folic acid alters expression of gene in the cerebellum of offspring-a pilot study Brain Sciences  2015, PMID: 25629700

Barua S et al: Folic acid supplementation in pregnancy and implications in health and disease. J Biomed Sci. 2014, PMID: 25135350

Barua S et al: Increasing Maternal or Post-Weaning Folic Acid Alters Gene Expression and Moderately Changes Behavior in the Offspring. PLOS ONE 2014, PMID: 25006883

Barua S et al: Single-base resolution of mouse offspring brain methylome reveals epigenome modifications caused by gestational folic acid. Epigenetics & Chromatin, 2014, PMID: 24484737

Barua S et al : Molecular Basis for Strain Variation in the Saccharomyces cerevisiae Adhesin Flo11p. mSphere 2016, PMID: 27547826

Book Chapters:

Basu P, Hirshfield I and Barua S (July-2015): Overview of Biofilms and some key methods for their study. Practical Handbook of Microbiology, Third Edition CRC Press Taylor & Francis Group Chapter 46, 835-854.

Barua S, Basu P, Hirshfield I (2009): Overview of Biofilms and some key methods for their study. Practical Handbook of Microbiology, Second Edition CRC Press Taylor & Francis Group Chapter 42, 675-685.

Platform presentation & Talk

Concurrent somatic 9p21 deletion and germline EP300 mutation in a patient with Gamma-Delta T Cell Acute Lymphoblastic Leukemia, immunodeficiency, global developmental delay, and multiple malformations: pure coincidence? (American College of Medical Genetics, Nashville :2022)

Targeted sequencing panel in Retinal disorder, New York Presbyterian, Children Hospital (CUIMC); August 2020.

Whole Exome sequencing: Nemaline myopathy, New York Presbyterian, Children Hospital; March 2019.

Stem-Loop Inhibition-Mediated amplification (SLIMamp) technology for interrogation of variants in tumors with limited diagnostic material, Dept of Pathology, Columbia University Medical Center, May 2019.

Columbia Personalized Genomic Medicine Journal Club: various articles, July 2018- June 2021.

Maternal Folic Acid: Too Much or Too Little? Implications in Birth Defects:  Subit Barua,   Ph.D.; Structural Neurobiology Laboratory, Department of Developmental Biochemistry, New York State Institute for Basic Research, March 2014.

Mechanism of Flo11 adhesion. Tulane Cancer Center, Tulane University School of   Medicine, May 2012.

Strain-specific regulation of FLO11-dependent flocculation. Speaker, Barua Subit, Fall    2010, Dept    of Biological Sciences, St John’s University, NY, March 2012.

Mechanism of adhesion as revealed by strain variation in Flo11 in yeast. Department of Biological Sciences, Brooklyn College, CUNY (invited by Prof P N. Lipke (Chairman, Department of Biological Sciences, Brooklyn College, CUNY, NY), April, 2011.

The Young Investigator Award at the Association of Molecular Pathology (AMP), 25th Year conference, Baltimore, USA, 2019.

Travel award at Yeast Cell Biology Meeting, Cold Spring Harbor, N.Y. August, 2009.

Medical Specialties

• Molecular Pathology

Board Certifications

• Clinical Cytogenetics, American Board of Medical Genetics
• Clinical Molecular Genetics, American Board of Medical Genetics
• DABMGG, Diplomat of American Board of Medical Genetics and Genomics

Special Training

• Fellowship, Genomics & Epigenetics
  New York State Office of Mental Retardation and Developmental Disabilities (OMRDD, NYSIBR), 2015
• Fellowship, Laboratory Genetics and Genomics
  Columbia University Irving Medical Center, NY, USA