Marieta Gencheva, PhD

Teaching Assistant Professor

Organization:

West Virginia University School of Medicine

Department:

Biochemistry and Molecular Medicine

Classification:

Faculty

Sanzhaeva U, Poncelet M, Tseytlin O, Tseytlin M, Gencheva M, Eubank TD, Khramtsov VV, Driesschaert B. Synthesis, Characterization, and Application of a Highly Hydrophilic Triarylmethyl Radical for Biomedical EPR. J Org Chem. 2020 Aug 21;85(16):10388-10398. doi: 10.1021/acs.joc.0c00557. 

Steinberger KJ, Forget MA, Bobko AA, Mihalik NE, Gencheva M, Roda JM, Cole SL, Mo X, Hoblitzell EH, Evans R, Gross AC, Moldovan L, Marsh CB, Khramstov VV, Eubank TD. Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer. J Immunol. 2020 Oct 15;205(8):2301-2311. doi: 10.4049/jimmunol.2000185. 

Dakhlallah DA, Wisler J, Gencheva M, Brown CM, Leatherman ER, Singh K, Brundage K, Karsies T, Dakhlallah A, Witwer KW, Sen CK, Eubank TD, Marsh CB. Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock. J Extracell Vesicles. 2019 Sep 28;8(1):1669881. doi: 10.1080/20013078.2019.1669881. 

Hare I, Gencheva M, Evans R, Fortney J, Piktel D, Vos JA, Howell D, Gibson LF. In Vitro Expansion of Bone Marrow Derived Mesenchymal Stem Cells Alters DNA Double Strand Break Repair of Etoposide Induced DNA Damage. Stem Cells Int. 2016;2016:8270464. doi: 10.1155/2016/8270464. 

Zang S, Lin TY, Chen X, Gencheva M, Newo AN, Yang L, Rossi D, Hu J, Lin SB, Huang A, Lin RJ. GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo. Biosci Rep. 2014 Dec 12;34(6):e00163. doi: 10.1042/BSR20140142. 

Gencheva M, Hare I, Kurian S, Fortney J, Piktel D, Wysolmerski R, Gibson LF. Bone marrow osteoblast vulnerability to chemotherapy. Eur J Haematol. 2013 Jun;90(6):469-78. doi: 10.1111/ejh.12109. 

Gencheva M, Yang L, Lin GB, Lin RJ. Detection of Alternatively Spliced or Processed RNAs in Cancer Using Oligonucleotide Microarray. Cancer Treat Res. 2013;158:25-40. doi: 10.1007/978-3-642-31659-3_2. PMID: 24222353

Rellick SL, Piktel D, Walton C, Hall B, Petros W, Fortney JE, Gencheva M, Denvir J, Hobbs G, Craig M, Gibson LF. Melphalan exposure induces an interleukin-6 deficit in bone marrow stromal cells and osteoblasts. Cytokine. 2012 May;58(2):245-52. doi: 10.1016/j.cyto.2012.01.012. 

Rellick SL, O'Leary H, Piktel D, Walton C, Fortney JE, Akers SM, Martin KH, Denvir J, Boskovic G, Primerano DA, Vos J, Bailey N, Gencheva M, Gibson LF. Bone marrow osteoblast damage by chemotherapeutic agents. PLoS One. 2012;7(2):e30758. doi: 10.1371/journal.pone.0030758. 

Dery KJ, Gaur S, Gencheva M, Yen Y, Shively JE, Gaur RK. Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M. J Biol Chem. 2011 May 6;286(18):16039-51. doi: 10.1074/jbc.M110.204057. 

Gencheva M, Chen CJ, Nguyen T, Shively JE. Regulation of CEACAM1 transcription in human breast epithelial cells. BMC Mol Biol. 2010 Nov 4;11:79. doi: 10.1186/1471-2199-11-79.