Qian

Yong Qian, PhD

Adjunct Assistant Professor

Contact

Send an Email
Phone
304-285-6286
Fax
304-285-5938
Address
NIOSH
Morgantown, WV
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Positions

Adjunct Assistant Professor

Organization:
School of Medicine
Classification:
Adjunct Faculty

Organization:
School of Public Health
Classification:
Adjunct Faculty

Publications

1.  Sisler JD, Pirela S, Friend S, Farcas MT, Schwegler-Berry DE, Shvedova AA, Castranova V,  

       Demokritou P, Yong Qian*.  2015

      Small airway epithelial cells exposure to printer emitted nanoparticles induces cellular effects on

      human microvascular endothelial cells in an alveolar-capillary co-culture model.  

      Nanotoxicology.  9(6):769-79.*Corresponding author

 

2. Talkington BN, Dong C, Zhao X, Dymacek J, Porter DW, Wolfarth M, Castranova V, Yong

      Qian*, Guo NL. 2015.

      Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies.     

      Toxicology.  3;328:66-74.  *Corresponding author

 

3. Dymacek J, Talkington BN, Porter DW, Wolfarth M, Castranova V, Yong Qian, Guo NL. 2015.

      mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung 

      inflammatory and fibrotic pathologies in mice.

      Toxicol Sci.   144(1):51-64. 

 

4. Mihalchik AL, Ding W, Porter DW, McLoughlin CE, Schwegler-Berry DE, Sisler JD, Stefaniak A,

     Talkington BN, Tsuruoka S, Endo M, Castranova V, Yong Qian*. 2015

     Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled 

      carbon nanotubes on human small airway epithelial cells .

      Toxicology.  333:25-36. *Corresponding author

 

5. Talkington BN, Dong C, Sargent LM, Porter DW, Raese R, McKinney W, Chen BT, Battelli L,

      Lowry D,  Reynolds SH,  Castranova V, Yong Qian*and Guo NL  2016

      mRNAs and miRNAs in whole blood associated with MWCNT-induced lung hyperplasia, fibrosis,

      and bronchiolo-alveolar adenoma and adenocarcinoma following inhalation exposure in mice. 

      *Corresponding author

      Journal of Applied Toxicology.  36(1):161-74.

 

6. Pirela SV, Miousse IR, Lu X,  Castranova V, Thomas T,  Yong Qian,  Bello D, Kobzik L,

       Koturbash L, Demokritou P. 2016.

       Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine

       Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive

       in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.      

       Environmental Health Perspectives. 124(2):210-9.

 

7. Pirela SV, Lu X, Miousse L, Sisler JD, Yong Qian, Guo, N, Koturbash I, Castranova V, Thomas

      T, Godleski J, and Demokritou P. 2016

       Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model:

       A case study of toxicological implications from nanomaterials released during consumer use      

       NanoImpact.  1(2016):1-8

 

8. Sisler JD, Pirela SV, Shaffer J,  Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, 

      Demokritou P, and Yong Qian* 2016 

      Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway        

      Epithelial Cells.

      Toxicological Sciences 150(2):418-28.  *Corresponding author  

 

9. Snyder-Talkington BN, Dong C, Porter DW, Ducatman B, Wolfarth MG, Andrew ME, Battelli L,

      Raese R, Castranova V, GuoNL, and Yong Qian*   2016

      Multi-walled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and

      genomic changes following aspiration exposure in mice: a 1-year post-exposure study.

       Journal of Toxicology and Environmental Health.  2016 79(8):352-66 *Corresponding author

 

10. Sisler JD, Li R, McKinney W, Mercer RR, Ji Z,  Xia Z, Wang X, Shaffer J, Orandle M,

      Mihalchik A, Battelli,  Chen T, Wolfarth MG,  Andrew ME, Schwegler-Berry D,  Porter DW,

      Castranova V, Nel A, and Yong Qian* 2016

      Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during

      aerosolized inhalation in mice.

      Particle and Fibra Toxicology 13(1):42.  *Corresponding author

 

 

11.  Mercer RR,  Scabilloni JF,  Wang L, Battelli LA,  Antonini JM,  Roberts JR,  Yong Qian, Sisler

       JD, Castranova V, Porter DW,  Hubbs AF. 2018

       The fate of inhaled nanoparticles: detection and measurement by enhanced darkfield microscopy.

       Toxicologic Pathology.  46(1):28-46

 

12.  Zhao J, Zhang Y, Sisler SD, Shaffer J, Leonard SS,  Morris AM, Yong Qian, Bello D,

       Demokritou D. 2018

       Assessment of reactive oxygen species generated by electronic cigarettes using acellular and

       cellular approaches.

       Journal of Hazardous Materials. 344:549-57

 

13.  Sisler SD, Qi Q, McKinney W,  Shaffer J,  Andrew M, Lee L, Thomas T, Castranova V, Mercer

       RR, and Yong Qian*.  2018

       Physical Chemical Properties and Cell Toxicity of Sanding Copper-Treated Lumber

       Journal of Occupational and Environmental Hygiene.15(4):311-321

       *Corresponding Author.

 

14. Chalbot MG, Pirela SV, Schifman L, Kasaraneni V, Oyanedel-Craver V, Bello D,  Castranova V,

      Yong Qian, Thomas T, Kavouras IG, Demokritou P.  2017

      Synergistic effects of engineered nanoparticles and organics released from laser printers using

      nano-enabled toners: potential health implications from exposures to the emitted organic aerosol.

      Environmental Science: Nano.  4(11):2144-2156

 

15.  Sisler SD, Shaffer J, Soo J,  Lebouf R, Harper M, Yong Qian*  and Lee T.  2018

       In vitro toxicological evaluation of surgical smoke from human tissue.

       Journal of Occupational and Environmental Hygiene. 13:12.  *Corresponding

      Author.

 

16.  Dymacek J, Snyder-Talkington B, Dong C, Singh S, Rease R, Porter D, Ducatman B, Wolfarth M,

       Andrew M, Battelli L, Castranova V, Yong Qian, Guo N. 2018.

       Similar and differential canonical pathways and biological processes associated with multi-walled

       carbon nanotube and asbestos-induced pulmonary fibrosis: a 1-year post-exposure study .

       Int J Toxicol.  37(4)276-284

 

17.  Guo NL, Dowlati A, Beer DG, Raese RA, Dong C, Chen G, Sfhffer J, Singh S, Bokhary U, Liu L,

       Howington J  and Yong Qian.  2018

       A predictive 7-gene assay and prognostic protein biomarkers for non-small lung cell lung cancer

       EBioMedicine.  32:102-110

 

18.  Stefaniak AB, Bowers LN, Knepp AK, Virji MA, Birch ME, Ham JE, Wells JR, Qi C, Schwegler-

       Berry D, Friend S, Johnson AR, Martin JB, Yong Qian, LeBouf RF, Hammond D. 2018

       3-dimensional printing with nano-enabled filaments releases polymer particles containing carbon

       nanotubes into air

       Indoor Air.  28(6):840-851

 

19. Sisler j, Mandler WK, Shaffer J, Lee T, McKinney W, Battelli L, Orandle M, Thomas T,

      Castranova V, Qi C, Porter D, Andrew m, Fedan J, Mercer R, and Yong Qian*.  2019

      Toxicological Assessment of Dust from Sanding Micronized Copper-Treated Lumber In Vivo.

      Journal of Hazardous Materials.  373:630-639    *Corresponding Author.

 

20. Kang S, Liang H, Yong Qian and Qi C.  2019

      The composition of emissions from sawing corian®, a solid surface composite material.

      Annals of Work Exposures and Health.  63(4): 480-483

 

21. Mandler WK, Qi C, Orandle MS, Sarkisian K, Mercer RR, Stefaniak AB, Knepp AK, Bowers LN,

      Battelli LA, Shaffer J, Friend SA, Yong Qian*, and Sisler JD. 2019

      Mouse pulmonary response to dust from sawing Corian®, a solid-surface composite material.

      Journal of Toxicology and Environmental Health, Part A. 82(11):645-663.   *Corresponding

      Author.

 

22. Snyder-Talkington BN, Dong C, Castranova V, Yong Qian and Guo NL. 2019

      Differential gene expression in human small airway epithelial cells grown in monoculture versus

      coculture with human microvascular endothelial cells following multiwalled carbon nanotube

      exposure.

      Toxicology Reports 6:482-488

 

23. Snyder-Talkington BN, Song C, Singh S, Raese R, Yong Qian, Porter DW, Wolfarth MG and Guo

      NL. 2019

      Multi-walled Carbon Nanotube-Induced Gene Expression Biomarkers for Medical and 

      Occupational Surveillance.

      International Journal of Molecular Sciences. 20(11):2635

 

24. Farcas MT, Stefaniak AB, Knef A, Bowers L, Mandler WK, Jackson S, Stueckle TA, Sisler JD,

      Friend SA, Qi C, Hammond D, Kashon M, Thomas TA, Matheson J. and Yong Qian*. 2019

      Three-dimensional (3-D) printer emission-induced cell toxicity.

      Toxicology Letters  25;317:1-12  *Corresponding Author.

 

25.  Guo NL, Pirela S, Farcas M, Poh TY, Chotirmall Sh, Tham Wk, Adav SS, Wang Y, Ng KW, Ye

       Q, Thomas T, Yong Qian, and Demokritou P.  2019

       Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum  

       for assessment of laser printer-emitted particles inhalation exposure-induced disease risk.

       Internal Journal of Molecular Sciences.  20(24):6348

 

26.  Carll AP, Salatini R, Pirela SV, Wang Y, Xie Z, Lorkiewicz P, Naeem N, Yong Qian, Castranova 

       V, Godleski JJ, and Deomokritou P. 2020

       Inhalation of Printer-Emitted Particles Impairs Cardiac Conduction, Hemodynamics, and 

       Autonomic Regulation and Induces Arrhythmia in Conscious Rats.

       Particle and Fibra Toxicology. 2020 17(1):7

 

27.  Mandler WK, Kang S, Farcas M, QI C, Sherri AF, and Yong Qian*. 2020

       In vitro toxicity assessment of respirable solid surface composite sawing particles

       *Corresponding Author.

       Toxicol Ind Health. 36(4):250-262

 

28. Farcas MT, McKinney W, Qi C, Mandler WK, Battelli L, Friend SA, Stefaniak AB, Jackson M,

      Orandle M, Winn A, Kashon M, LeBouf RF, Hammond DR, Burns D, Ranpara A, Thomas TA,

      Matheson J, Yong Qian*    2020         *Corresponding Author.

      Pulmonary and systemic toxicity in rats following inhalation exposure of  3-D printer emissions

      from acrylonitrile butadiene styrene (ABS) filament.

      Inhalation Toxicology . 32(11-12):403-418

 

29.  Kang S, Liang H, Yong Qian, and Qi C. 2021  The Composition of Emissions from Sanding

       Corian® with Different Sandpapers.

       Aerosol and Air Quality Research.  21(2):200377

Additional Info

Research Projects (ongoing)

  1. pulmonary and autoimmune responses to aerosolized emissions from 3-D printers
  2. toxicological assessment of emission from fabricating engineered stone countertop

Research Interests

Research Projects (ongoing)

  1. pulmonary and autoimmune responses to aerosolized emissions from 3-D printers
  2. toxicological assessment of emission from fabricating engineered stone countertop