About William Stauber
William T. Stauber, PT, Ph.D., FACSM Professor of Physiology and Pharmacology West Virginia University Morgantown, WV 26506-9229 Born in East Orange, New Jersey, William Stauber received degrees from Ithaca College (B.S., Physical Therapy) and R...
- MS, Rutgers University, New Brunswick(Dr. John W.C. Bird), NJ, 1969
- BS, Physical Therapy (Magna Cum Laude), Ithaca College, Ithaca, NY, 1967
- PhD, Rutgers University (Dr. John W.C. Bird), New Brunswick, NJ, 1972
- Selected peer-reviewed publications (in chronological order).
(Publications selected from 89 peer-reviewed publications)
1. Stauber, W.T., Fritz, V.K., Clarkson, P.M. and J.E. Riggs. 1991. An injury myopathy mimicking dystrophy: Implications regarding the function of dystrophin. Med. Hypotheses. 35: 358-362.
2. Stauber, W.T., G.R. Miller, J.G. Grimmett and K.K. Knack. 1994. Adaptation of rat soleus muscles to intermittent chronic strain. J. Appl. Physiol. 71:58-62.
3. Gibala, M.J., MacDougall, J.D., Tarnopolsky, M.A., Stauber, W.T. and A. Elorriaga. 1995. Changes in human skeletal muscle ultrastructure and force production after acute resistance exercise. J. Appl. Physiol. 78(2): 702-708.
4. Stauber, W.T., Miller, G.R., Gibala, M.J., and J.D. MacDougall. 1995. Use of double labeling and photo CD for morphometric analysis of injured skeletal muscle. J. Histochem. Cytochem. 43 (11): 1179-1184.
5. Stauber, W.T. Delayed Onset Muscle Soreness, In: Athletic Injuries and Rehabilitation, Zachazewski, J., Magee, D., and W. Quillen (eds), Saunders, Philadelphia, PA, 1996, pp. 92-98.
6. Stauber, W.T., Knack, K.K., Miller, G.R., and J.G. Grimmett. 1996. Fibrosis and intercellular collagen connections from four weeks of muscle strains. Muscle & Nerve 19: 423-430.
7. Cutlip, R.G., Stauber, W.T., Willison, R.H., McIntosh, T.A., and K.H. Means. 1997. A dynamometer for the measurement of rat plantar flexor muscles in vivo. Med. Biol. Engin. & Comput. 35: 540-543.
8. Stauber, W.T., and C.A. Smith. 1998. Cellular responses in exertion-induced skeletal muscle injury. Molecular Cell. Biochem. 179: 169-176.
9. Stauber, W.T., Miller, G.R., and J.G. Grimmett. 1998. Adaptation of rat gastrocnemius muscles to 2 wk of centrifugation: Myofibers and Matrix. Aviation, Space Environ. Med. 69(6) Suppl: A45-A48.
10. Willems, M. E.T. and W. T. Stauber. 1999. Static and dynamic actions of rat plantar-flexor muscles in vivo. Exp. Physiol. 84: 379-389.
11. Miller, G.R., Smith, C.A. and W. T. Stauber. 1999. Determination of fibrosis from cryostat sections using high performance liquid chromatography: Skeletal muscle. Histochem. J. 31: 89-94.
12. Willems, M. E. T. and W.T. Stauber. 2000. Force output during and following active stretches of rat plantar flexor muscles: effect of velocity of ankle rotation. J Biomech 33: 1035-1038.
13. Stauber, W.T., Barill, E.R., Stauber, R.E., and G.R. Miller. 2000. Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females. Clinical Physiology 20: 225-233.
14. Willems, M. E. T. and W.T. Stauber. 2000. Performance of plantar flexor muscles with eccentric and isometric contractions in intact rats. Med Sci Sports Exerc 32 (7): 1293-1299.
15. Willems, M. E. T. and W.T. Stauber. 2000. Effect of resistance training on muscle fatigue and recovery in intact rats. Med Sci Sports Exerc 32 (11): 1887-1893.
16. Stauber, W.T., Smith, C.A., Miller, G.R., and Stauber, F.D. 2000. Recovery of rat soleus muscles from 6 weeks of repeated strain injury. Muscle & Nerve 23: 1819-1825.
17. Willems, M. E. T. and W.T. Stauber. 2000. Changes in force by repeated stretches of skeletal muscle in female Sprague Dawley rats. Aging: Clinical and Experimental Research 12: 478-481.
18. Willems, M. E. T. and W.T. Stauber. 2000. Force during stretches of rat skeletal muscles after hypertonia at short and long lengths. Arch. Physiol. Biochem.108: 391-397.
19. Willems, M. E. T., Miller, G.R. and W.T. Stauber. 2001. Force deficits after stretches of activated rat muscle-tendon complex with reduced collagen cross-links. Euro. J. Appl. Physiol. 85: 405-411.
20. Willems, M. E. T. and W.T. Stauber. 2001. Force deficits after repeated stretches of activated skeletal muscle in female and male rats. Acta Physiologica Scand.172: 63-67.
21. Willems, M. E. T. and W.T. Stauber. 2002. Force deficits by stretches of activated muscles with constant or increasing velocity. Med. Sci. Sports Exerc. 34: 667-672.
22. Willems, M. E. T. and W.T. Stauber. 2002. Effect of contraction history on torque deficits by stretches of active rat skeletal muscles. Cand. J. Appl. Physiol. 27: 323-335.
23. Willems, M. E. T. and W.T. Stauber. 2002. Fatigue and recovery at long and short muscle lengths following resistance training. Med. Sci. Sports & Exerc. 34: 1738-1743.
24. Stauber, W.T. and M.E.T. Willems. 2002. Prevention of histopathologic changes from 30 repeated stretches of active rat skeletal muscles depends on inter-stretch rest time. Eur. J. Appl. Physiol. 88: 94-99.
25. Willems, M.E.T. and W.T. Stauber. 2003. Attenuation of stretch-induced histopathologic changes of skeletal muscle by quinacrine. Muscle & Nerve 27: 65-71.
26. Stauber, W.T. 2004. Factors involved in strain-induced injury in skeletal muscles and outcomes of prolonged exposures. J. Electromyography & Kinesiology 14 (1): 61-70.
27. Smith, C.S., Waters, C., Always, S.E., Stauber, F.D. and W.T. Stauber. 2007. Transforming growth factor beta following skeletal muscle strain injury. J Appl Physiol 102: 755–761.
28. Hickman, D. M. and W.T. Stauber. 2007. Mapping mandibular rest in humans utilizing electromyographic patterns from masticatory muscles. J. Craniomandibular Practice 25(4): 264-272.
29. Willems, M.E.T. and W.T. Stauber. 2009. The effect of number of lengthening contractions on rat isometric force production at different frequencies of nerve stimulation. Acta Physiologica 196: 351-356.
30. Willems, M.E.T., Gerald R. Miller, G.R., Stauber, F.D. and W.T. Stauber. 2010. Effects of repeated lengthening contractions on skeletal muscle adaptations in female rats. J. Physiol. Sci. 60: 143-150.
31. Pistilli, E.E., Guo, G. and W.T. Stauber. 2012. 3IL-15Rα Deficiency leads to mitochondrial and myofiber differences in fast mouse muscles. Cytokine 61: 41-45.
Honors and Awards.
North American Life Research Award for a study on knee dysfunction (1985),
Fellow of the American College of Sports Medicine (1987),
Nominated for Distinguished Teacher Award WVU (1990, 1991),
Cosmos Biosatellite Team, Group Achievement Award (NASA 1991),
Cosmos 2G Comparison Study Team, Group Achievement Award (NASA 1994),
Honorary Fellow of the International College of Craniomandibular Orthopedics (1995),
Invited speaker for the Steven Rose Memorial Lecture, Washington University, St. Louis, MO, for lifetime research contributions to Physical Therapy (1999),
Nominated for the John W. Traubert Award (2001),
Benedum Distinguished Scholar Award, West Virginia University, April, 2002.
Other Experience and Professional Memberships
President, Comptex, Inc., 1982-2003 (Corp. was dissolved 4/2003).
Grant reviewer for NIH (ad hoc member of SEPs), NIOSH, NSF, NASA, DoD and private foundations as well as a manuscript reviewer for a wide variety of research journals.
Chairman of the Scientific/Medical Advisory Committee of MEDigital, Inc., Marietta, GA, 2000-2003.
About William Stauber
Dr. Stauber became part of the PT teaching faculty in 1993. Dr. Stauber reviews manuscripts for a number of prominent journals, and received many awards becoming a Fellow of the American College of Sports Medicine in 1987. In 2002, he received the Benedum Distinguished Scholar Award. He has an active research laboratory and has been continuously funded by NIOSH/CDC for the past 10 years.
Current collaborators: Cheryl A. Smith, Ph.D. (WVU).
- Stauber, W.T., Barill, E.R., Stauber, R.E., and G.R. Miller. 2000. Isotonic dynamometry for the assessment of power and fatigue in the knee extensor muscles of females. Clin. Physiol. 20: 225-233.
- Willems, M. E. T. and W.T. Stauber. 2000. Performance of plantar flexor muscles with eccentric and isometric contractions in intact rats. Med. Sci. Sports Exerc. 32: 1293-1299.
- Willems, M. E. T. and W.T. Stauber. 2000. Effect of resistance training on muscle fatigue and recovery in intact rats. Med. Sci. Sports Exerc. 32: 1887-1893. · Stauber, W.T., Smith, C.A., Miller, G.R., and F.D. Stauber. 2000. Recovery of rat soleus muscles from 6 weeks of repeated strain injury. Muscle & Nerve 23: 1819-1825.
- Willems, M. E. T. and W.T. Stauber. 2000. Changes in force by repeated stretches of skeletal muscle in female Sprague Dawley rats. Aging: Clin. Exp. Res. 12: 478-481.
- Willems, M. E. T. and W.T. Stauber.2000. Force during stretches of rat skeletal muscle after hypertonia at short and long lengths. Archiv. Physiol. Biochem. 108: 391-397.
- NIOSH/CDC Grant R01 OH 02918 Cumulative Trauma Disorder: Skeletal Muscle Dysfunction. 6/01-5/04. $600,000. Principle Investigator.
PT 425 - Physical Therapy Procedures II (lecturer - resistance training)
PT 420 - Therapeutic Physical Agents (lecturer - electrotherapy)
PT 591 - Special Topics (lecturer - electrodiagnosis and surface EMG)
Positions and Employment
1976-1979 Associate, Department of Physiology and Biophysics, University of Iowa
1979-1981 Assistant Professor, Department of Physiology, West Virginia University, College of Medicine
1981-1985 Associate Professor, Department of Physiology, West Virginia University, College of Medicine
1984-1985 Associate Professor, Department of Neurology, West Virginia University, College of Medicine
1985-1994 Professor, Departments of Physiology and Neurology, West Virginia University, Hlth. Sci. Ctr.
1994-Pres. Professor, Departments of Physiology and Pharmacology, Neurology and the Division of Physical Therapy, West Virginia University, Robert C. Byrd Health Sciences Center.
Muscle physiology, exercise physiology, repetitive stress injuries, muscle injury and repair, and muscle fibrosis and movement dysfunction.
The effects of acute and chronic muscle strain injuries such as experienced in occupations where movements involving deceleration of body segments are studied. Skeletal muscle atrophy, growth and repair are common in strain-injured muscles. The importance of the extracellular matrix, material surrounding the muscle cells, as a control site for growth and repair is of special interest because fibrosis can develop from repeated injuries. Muscle fibrosis, which is the proliferation of collagen, can produce muscle dysfunction - often seen in muscle contractures. We built a rodent dynamometer to test the dynamic parameters (force, velocity, dose) involved in producing strain injuries in rats and to record changes in muscle strength and fatigue. Our studies revealed that complex interactions of functional parameters important in producing either a hypertrophic or fibrotic muscle. Knowledge of the parameters involved in muscle strain injuries is important in developing prevention strategies to improve worker health and well being.