Karen Martin , PhD

Service Professor

Organization:

West Virginia University School of Medicine

Department:

Microbiology, Immunology & Cell Biology

Classification:

Faculty

Member

Organization:

West Virginia University WVU Cancer Institute

Department:

WVU Cancer Institute Research Programs

Classification:

Faculty

Core Director

Organization:

West Virginia University WVU Cancer Institute

Department:

WVU Cancer Institute Research Laboratories

Classification:

Faculty

Director of Core Resources

Organization:

West Virginia University Health Sciences Center

Department:

Research & Graduate Education

Classification:

Admin

• PhD, Duke University Medical Center, 1997

Geldenhuys WJ, Piktel D, Moore JC, Rellick SL, Meadows E, Pinti MV, Hollander JM, Ammer AG, Martin KH, Gibson LF. Loss of the redox mitochondrial protein mitoNEET leads to mitochondrial dysfunction in B-cell acute lymphoblastic leukemia. Free Radic Biol Med. 2021; 175: 226-35. PMCID: PMC8478879.

Rellick SL, Hu G, Piktel D, Martin KH, Geldenhuys WJ, Nair RR, Gibson LF. Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease. Sci Rep. 2021; 11(1): 15840. PMCID: PMC8339057.

Sizemore G, McLaughlin S, Newman M, Brundage K, Ammer A, Martin K, Pugacheva E, Coad J, Mattes MD, Yu HG. Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer. BMC Cancer. 2020; 20(1): 595. PMCID: 7318490.

Nair RR, Piktel D, Hathaway QA, Rellick SL, Thomas P, Saralkar P, Martin KH, Geldenhuys WJ, Hollander JM, Gibson LF. Pyrvinium pamoate use in a B cell acute lymphoblastic leukemia model of the bone tumor microenvironment. Pharm Res. 2020; 37(3): 43. PMCID: 7021357.

Geldenhuys WJ, Nair RR, Piktel D, Martin KH, Gibson LF. The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia. J Pharmacol Exp Ther. 2019; 370(1): 25-34. PMCID: 6538890.

Yu HG, McLaughlin S, Newman M, Brundage K, Ammer A, Martin K, Coad J. Altering calcium influx for selective destruction of breast tumor. BMC Cancer. 2017; 17(1): 169. PMCID: 5336649.

Moses BS, Slone WL, Thomas P, Evans R, Piktel D, Angel PM, Walsh CM, Cantrell PS, Rellick SL, Martin KH, Simpkins JW, Gibson LF. Bone marrow microenvironment modulation of acute lymphoblastic leukemia phenotype. Exp Hematol. 2016; 44(1): 50-9 e1-2. PMCID: 4684957.

Slone WL, Moses BS, Evans R, Piktel D, Martin KH, Petros W, Craig M, Gibson LF. Modeling chemotherapy resistant leukemia in vitro. J Vis Exp. 2016; (108): e53645. PMCID: 4781739.

Cowen S, McLaughlin SL, Hobbs G, Coad J, Martin KH, Olfert IM, Vona-Davis L. High-fat, high-calorie diet enhances mammary carcinogenesis and local inflammation in MMTV-PyMT mouse model of breast cancer. Cancers (Basel). 2015; 7(3): 1125-42. PMCID: PMC4586761.

Bruce A, Evans R, Mezan R, Shi L, Moses BS, Martin KH, Gibson LF, Yang Y. Three-dimensional microfluidic tri-culture model of the bone marrow microenvironment for study of acute lymphoblastic leukemia. PLoS One. 2015; 10(10): e0140506. PMCID: 4619215.

Non-Programmatically Aligned Cancer Center Members