Jesse McClure, MD

Resident

Organization:

West Virginia University School of Medicine

Department:

Neurosurgery

Classification:

Resident

• MD, University of Virginia School of Medicine, 2023

• McClure J, Zhang C, Inks E, Peterson Y, Li J, Chou C. Development of Allosteric Hydrazide- Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia. J. Med. Chem.
• McClure J, Inks E, Zhang C, Peterson Y, Li J, Chundru K, Lee B, Buchanan A, Miao S, Chou C. Comparison of the Deacylase and Deacetylase Activity of Zinc-Dependent HDACs. ACS Chem. Biol.
• McClure J, Li X, Chou CJ. Advances and Challenges of HDAC Inhibitors in Cancer Therapeutics. Adv. Cancer Res.
• McClure J, Palanisamy V. Muscle-Specific FXR1 Isoforms in Squamous Cell Cancer. Trends Cancer.
• McClure J, Desai BD, Shabo LM, Buell TJ, Yen CP, Smith JS, Shaffrey CI, Shaffrey ME, Buchholz AL.
• A single-center retrospective analysis of 3- or 4-level anterior cervical discectomy and fusion: surgical outcomes in 66 patients. J. Neurosurg. Spine.
• McClure J, Desai BD, Ampie L, You W, Smith JS, Buchholz AL. A Systematic Review of the Cost- Utility of Spinal Cord Stimulation for Persistent Low Back Pain in Patients With Failed Back Surgery Syndrome. Global Spine J.
• Rabinovich EP, Snyder MH, McClure J, Buell TJ, Smith JS, Shaffrey CI, Buchholz AL. Posterior Polyethylene Tethers Reduce Occurrence of Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity: A Retrospective Analysis. Neurosurgery.
• McClure J, Jentoft M, Sandhu S, Chen S, Abode-Iyamah K. Bone-Anchored Annular Closure Device Leading to Histiocytic-Inflammation-Induced Neuropathy with Resolution after Removal: A Case Report. European Spine Journal.
• Bean L, Goon M, McClure J, Aguiar R, Kato N, DiMarzio M, Pilitsis J. The Evolution of Surgical Technique in Spinal Cord Stimulation: A Scoping Review. Operative Neurosurgery.
• McClure J, Chatrath A, Robison T, Jane Jr. J. Conditioned recurrence-free survival following gross-total resection of nonfunctioning pituitary adenoma: a single-surgeon, single-center retrospective study. Journal of Neurosurgery.
• Mayer R, Desai K, Aguiar R, McClure J, Kato N, Kalman C, Pilitsis J. Evolution of Deep Brain Stimulation Techniques for Complication Mitigation. Operative Neurosurgery.

My path to medical school and neurosurgery has been far from traditional. I grew up loving computers, chemistry, and tinkering. So, naturally, I became a drug dealer pharmacist. But that didn't quite fit, not to mention the constant hassles with the DEA. So, I switched gears from dealer to supplier and obtained a Ph.D. in Drug Discovery from the Medical University of South Carolina. I patented compounds, co-started and owned a biotech, and was granted an NIH-funded post-doctoral fellowship; but that didn't quite fit either. I realized my calling in life needed to combine patient care, the ability to research, and the ability to tinker with, utilize, and improve technology. The School of Medicine at the University of Virginia was where I happily landed. I found neurosurgery, and in particular for me, spine surgery, to be the perfect combination of patient care, research, and utilization of technology to fulfill my purpose in life. I was brought to WVU by its focus on innovative therapies, breadth and quality of research opportunities, early operative time and large operative volume to resident ratio, as well as being in perhaps the single best city associated with a neurosurgery residency to raise a family.