James J. Mahoney III , PhD

Associate Professor/Clinical Neuropsychologist

Organization:

West Virginia University School of Medicine

Department:

Behavioral Medicine & Psychiatry

Classification:

Faculty

Associate Professor

Organization:

West Virginia University School of Medicine

Department:

Department of Neuroscience

Classification:

Faculty

Associate Professor

Organization:

West Virginia University School of Medicine

Department:

Rockefeller Neuroscience Institute (SOM)

Classification:

Faculty

• PhD, University of Houston, 2014
• MA, Pepperdine University (Los Angeles, California), 2007

Research Manuscripts (Peer-Reviewed)

 

*Abbreviated list from 68 total peer-reviewed published manuscripts

 

Complete List of Published Works: https://www.ncbi.nlm.nih.gov/myncbi/189OsqqAyVeQS/bibliography/public/

 

1. Mahoney, III, J.J., Kalechstein, A.D., De Marco, A.P., Newton, T.F. & De La Garza, II, R. (2017). The relationship between premorbid IQ and neurocognitive functioning in individuals with cocaine use disorders. Neuropsychology, 31, 311-318.
2. Mahoney, III, J.J., Bajo, S.D., De Marco, A.P., Arredondo, B.C. & Broshek, D. K. (2017). Referring providers’ preferences and satisfaction with neuropsychological services. Archives of Clinical Neuropsychology, 32, 427-436.
3. Mahoney, III, J.J., Haile, C.N., De La Garza, II, R., Thakkar, H., & Newton, T.F. (2017). Electrocardiographic characteristics in individuals with cocaine use disorder. American Journal on Addictions, 26, 221-227.
4. Mahoney, III, J.J., Kalechstein, A.D., Newton, T.F. & De La Garza, II, R. (2017). The limited impact that cocaine use patterns have on neurocognitive functioning in individuals with cocaine use disorder. Journal of Psychopharmacology, 31, 989-995.
5. Mahoney, III, J.J. (2019). Cognitive Dysfunction in Individuals with Cocaine Use Disorder: Potential Moderating Factors and Pharmacological Treatments. Experimental and Clinical Psychopharmacology, 27, 203-214.
6. Mahoney, III, J.J., Marshalek, P.J., Rezai, A., Lander, L.R., Berry, J.H., & Haut, M.W. (2020). A Case Report Illustrating the Effects of Repetitive Transcranial Magnetic Stimulation on Cue-Induced Craving in an Individual with Opioid and Cocaine Use Disorder. Experimental and Clin. Psychopharmacology, 28, 1-5.
7. Mahoney, III, J.J., Hanlon, C.A., Marshalek, P.J., Rezai, A., & Krinke, L. (2020). Transcranial Magnetic Stimulation, Deep Brain Stimulation, and Other Forms of Neuromodulation for Substance Use Disorders: Review of Modalities and Implications for Treatment. Journal of Neurological Sciences, 418, 117149.
8. Mahoney, III, J.J., Winstanley, E., Lander, L.R., Berry, J.H., Marshalek, P.J., Haut, M.W., Marton, J., Kimble, W., Armistead, M., Wen, S., Cai, Y., & Hodder, S. (2020). High Prevalence of Co-Occurring Substance Use in Opioid Use Disorder.  Addictive Behaviors. 114, 106752.
9. Mahoney, III, J.J., Haut, M., Hodder, S., Zheng, W., Lander, L., Berry, J., Farmer, D.L., Marton, J.L., Brandmeir, N., Ranjan, M., Finomore, V., Hensley, J.L., Aklin, W.M., Wang, G., Tomasi, D., Shokri-Kojori, E., & Rezai, A. (2021). Deep Brain Stimulation of the Nucleus Accumbens/Ventral Capsule for Co-occurring Opioid and Benzodiazepine Use Disorder. Experimental and Clinical Psychopharmacology, 29, 210-215.
10. Mahoney, III, J.J., Koch-Gallup, N., Scarisbrick, D.M., & Rezai, A.R. (2022). Deep Brain Stimulation for Psychiatric Disorders and Behavioral/Cognitive-Related Indications: Review of the Literature and Implications for Treatment. Journal of Neurological Sciences, 437, 120253.

Additional Information

 

Academic Honors

 

2016     University of Virginia – Scientist-Practitioner Scholar Fellowship Award

2017    American Psychological Association, Division 28 – Young Psychopharmacologist Award

2017    West Virginia University School of Medicine – Chairman’s Research Award

2018    Bridgewater College – Young Alumnus Award

2019    Journal of Experimental and Clinical Psychopharmacology – Editorial Fellowship

2020    West Virginia University School of Medicine – Chairman’s Research Award

2022    WVU School of Medicine – Chancellor’s Outstanding Achievement in Research Award

 

 

Professional Abstracts

 

*Abbreviated list from 95 total professional abstracts

 

1. Keith, C., McCuddy, W., Nose, K., Lander, L., Haut, M., Berry, J., Harvey, D., Mahoney, III, J.J., (2019, February). The Relationship between Cognition and Potential Moderating Factors in Individuals with Opioid Use Disorder. International Neuropsychological Society, New York, NY.
2. Mahoney, III, J.J., Berry, J.H., Lander, L.R., Winstanley, E., Marshalek, P.J., Haut, M.W., Marton, J., Hodder, S., Kimble, W., Armistead, M. (2019, April).  The Prevalence of Poly-Substance Use among Psychiatric and Emergency Department Patients in West Virginia. Annual Meeting of the West Virginia Clinical and Translational Science Institute, White Sulphur Springs, WV.
3. Mahoney, III, J.J., Berry, J., Lander, L., Winstanley, E., Marshalek, P., Haut, M., Marton, J., Hodder, S., Kimble, W.(2019, June).  The Prevalence of Poly-Substance Use among Psychiatric and Emergency Department Patients in West Virginia. College on Problems of Drug Dependence,. San Antonio, TX.
4. Mahoney, III, J.J., Winstanley, E., Lander, L.R., Berry, J.H., Marshalek, P.J., Zheng, W., Marton, J., Haut, M.W. (2020, June). Something to Despair: Gender Differences in Adverse Childhood Experiences among Rural Patients. College on Problems of Drug Dependence [virtual meeting due to COVID-19 pandemic].
5. Mahoney, III, J.J., Haut, M., Hodder, S., Zheng, W., Lander, L., Berry, J., Brandmeir, N., Ranjan, M., Finomore, V., Wang, G., Tomasi, D., Shokri-Kojori, E., Rezai, A. (2021, May). Deep Brain Stimulation of the Nucleus Accumbens/Ventral Capsule for Co-occurring Opioid and Benzodiazepine Use Disorder. 2^nd Annual NIH Heal Initiative Investigator Meeting [virtual meeting due to COVID-19 pandemic].
6. Mahoney, III, J.J., Haut, M., Hodder, S., Zheng, W., Lander, L., Berry, J., Marton, J., Ranjan, M., Finomore, V., Farmer, D., Aklin, W., Wang, G., Tomasi, D., Shokri-Kojori, E., Rezai, A. (2022, April). Feasibility of Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder. 3^rd Annual NIH Heal Initiative Investigator Meeting [virtual meeting due to COVID-19 pandemic].
7. Mahoney, III, J.J., Haut, M., Carpenter, J., Zheng, W., Berry, J., Marton, J., Finomore, V., Rezai, A. (2022, June). Low Intensity Focused Ultrasound Targeting the Nucleus Accumbens as a Potential Adjunctive Treatment for Substance Use Disorder. College on Problems of Drug Dependence, Minneapolis, MN.
8. Marton, J., Farmer, D., Long, A., Winstanley, E., Finomore, V., Rezai, A., Mahoney, III, J.J. (2022, June). Assessing Changes in Cognitive Functioning in Individuals with Opioid Use Disorder Enrolled in a Residential Treatment Program. College on Problems of Drug Dependence, Minneapolis, MN.

 

 

 

 

Invited Lectures and Oral Presentations

 

*Abbreviated list from 23 invited lectures and oral presentations

 

1. Mahoney, III, J.J.  (2019, April).  Novel and Innovative Studies on Addiction Treatment. Oral presentation at the Annual Meeting of the WVCTSI. White Sulphur Springs, WV.
2. Mahoney, III, J.J., Berry, J.H. (2020, June). Rockefeller Neuroscience Institute: Substance Use Disorder Treatment Interventions. Oral presentation for the SAMHSA Region III Harm Reduction Summit [virtual meeting due to COVID-19 pandemic].
3. Mahoney, III, J.J., Haut, M., Hodder, S., Zheng, W., Lander, L., Berry, J., Brandmeir, N., Ranjan, M., Finomore, V., Wang, G., Tomasi, D., Shokri-Kojori, E., Rezai, A. (2020, June). Deep Brain Stimulation of the Nucleus Accumbens/Ventral Capsule for Co-occurring Opioid and Benzodiazepine Use Disorder. Oral presentation during the Late Breaking Research Session at the annual meeting of the College on Problems of Drug Dependence [virtual meeting due to COVID-19 pandemic].
4. Mahoney, III, J.J.  (2020, November). Novel and Innovative Studies on Addiction Treatment. Oral presentation at the Rural Drug Addiction Symposium on Substance Use Research [virtual conference due to COVID-19 pandemic].
5. Mahoney, III, J.J., Rezai, A.R. (2021, February). Neuromodulation for Substance Use Disorders: Invasive and Noninvasive Modalities. Oral presentation at the National Institute on Drug Abuse Intramural Research Program seminar series. Bethesda, MD.
6. Mahoney, III, J.J. (2021, March). Neuromodulation as an Adjunctive Treatment Strategy for Substance Use Disorders. Oral presentation at the Emerging Addiction Workshop, Columbia University, New York, NY.
7. Mahoney, III, J.J., Haut, M., Hodder, S., Zheng, W., Lander, L., Berry, J., Brandmeir, N., Ranjan, M., Finomore, V., Rezai, A. (2021, October). Deep Brain Stimulation of the Nucleus Accumbens/Ventral Capsule for Treatment Refractory Substance Use Disorder. Oral presentation during Opioid Awareness Week hosted by Weber State University, Ogden, Utah [virtual conference due to COVID-19 pandemic].
8. Mahoney, III, J.J. (2021, November). Preliminary Investigation of Low Intensity Focused Ultrasound Applied to the Nucleus Accumbens as a Potential Treatment for Substance Use Disorder: Impact on Substance Craving and Cognition. Oral presentation at the Rural Drug Addiction Symposium on Substance Use Research [virtual conference due to COVID-19 pandemic].
9. Mahoney, III, J.J. (2022, May). Ensuring that Participant Study-Related Needs Are Met Post-Trial Completion: Responsibilities of the Investigator/Investigative Team. Oral presentation during the BRAIN Neuroethics Working Group (NEWG) workshop on Continuing Trial Responsibilities, National Institute of Health [virtual conference].
10. Mahoney, III, J.J. (2022, May). Neuromodulation as an Adjunctive Treatment Strategy for Substance Use Disorders. Oral presentation during the Pathway to a Healthier Kentucky Conference hosted by the University of Kentucky Department of Physician Assistant Studies, Lexington, KY.

Research

 

Research Interests

 

My specific areas of research focus includes cognitive sequelae related to substance use as well as the investigation of various forms of neuromodulation, including deep brain stimulation, focused ultrasound, and transcranial magnetic stimulation for the treatment of substance use disorders. My current interests emerged from my previous research work as a Clinical Research Manager at the University of California, Los Angeles and the Baylor College of Medicine where the primary focus of the laboratories was Phase I medication development for stimulant use disorders. During this time, while the primary outcomes of the clinical trials were safety and initial efficacy of the medications, I was able to carve out my own niche that included evaluating whether these compounds impacted cognition as some of these agents had cognitive enhancing properties.

 

Research Topics:

 

1. Investigating Novel Treatments for Substance Use Disorder
2. Neuropsychological Sequelae Associated with Substance Use Disorder

 

Research Topics:

1. Investigating Novel Treatments for Opioid Use Disorder
2. Neuropsychological Sequelae Associated with Opioid Use Disorder

Special Training

• Fellowship, Clinical Neuropsychology Postdoctoral Fellowship (APPCN Member)
  University of Virginia School of Medicine, 2016
• Other Speciality Training, Clinical Psychology Internship - Neuropsychology Track
  University of Oklahoma Health Sciences Center, 2014