Director, Master of Science in Health Sciences
- West Virginia University Health Sciences Center
- Research & Graduate Education
- West Virginia University WVU Cancer Institute
- WVU Cancer Institute Research Programs
- PhD, West Virginia University, 1986
Khouj Y, Dawson J, Coad J, Vona-Davis LC. Hyperspectral imaging and K-means classification for histologic evaluation of ductal carcinoma in situ. Fron Oncol. 2018 Feb7:8:17. PMID: 29468139. https://www.ncbi.nlm.nih.gov/pubmed/29468139
Mattes MD, Swart E, Markwell SM, Wen S, Vona-Davis L. Methods of academic course planning for cancer biology PhD students to enhance knowledge of clinical oncology. Cancer Research 2017;77(18):4741-4744.PMID: 28729414. https://www.ncbi.nlm.nih.gov/pubmed/28729414
Mattes MD, Swart E, *Markwell SM, Wen S, Vona-Davis L. Methods of academic course planning for cancer biology PhD students to enhance knowledge of clinical oncology. Cancer Research 2017 1-4. PMID: 28729414 DOI: 10.1158/0008-5472.CAN-17-1057.
High-fat, high-calorie diet enhances mammary carcinogenesis and local inflammation in MMTV-PyMT mouse model of breast cancer.
Cowen S, McLaughlin SL, Hobbs GR, Coad JE, Martin KH, Olfert IM, Vona-Davis LC.
Cancers (Basel). 2015;7(3):1125-1142.
The interactions of obesity, inflammation and insulin resistance in breast cancer.
Rose DP, Gracheck PJ, Vona-Davis LC.
Cancers (Basel). 2015;7(4):2147-2168.
Exercise and dietary advice intervention for survivors of triple-negative breast cancer: effects on body fat, physical function, quality of life, and adipokine profile.
Swisher AK, Abraham J, Bonner D, Gilleland D, Hobbs GR, Kurian S, Yanosik MA, Vona-Davis LC.
Support Care Cancer. 2015;23(10):2995-3003.
Essential components of cancer education.
Welch DR, Antalis TM, Burnstein K, Vona-Davis LC, Jensen RA, Nakshatri H, Riegel AT, Spitz DR, Watson DK, Weiner GJ, Cancer Biology Training Consortium.
Cancer Res. 2015;75(24):5202-5205.
Loss of adipocyte VEGF impairs endurance exercise capacity in mice.
Zachwieja NJ, O'Connell GC, Stricker JC, Allen J, Vona-Davis LC, Bryner R, Mandler W, Olfert IM.
Med Sci Sports Exerc. 2015;47(11):2329-2339.
"Don't Know" and accuracy of breast cancer risk perceptions among Appalachian women attending a mobile mammography program: implications for educational interventions and patient empowerment.
Lemasters TJ, Madhavan SS, Atkins E, Vyas A, Remick SC, Vona-Davis LC.
J Cancer Educ. 2014;29(4):669-679.
Biochemical and molecular mechanisms for the association between obesity, chronic Inflammation, and breast cancer.
Rose DP, Vona-Davis LC.
Breast cancer pathology, receptor status, and patterns of metastasis in a rural Appalachian population.
Vona-Davis LC, Rose DP, Gadiyaram V, Ducatman BS, Hobbs GR, Hazard HW, Kurian S, Abraham J.
J Cancer Epidemiol. 2014;2014:170634
The obesity-inflammation-eicosanoid axis in breast cancer.
Vona-Davis LC, Rose DP.
J Mammary Gland Biol Neoplasia. 2013;18(3-4):291-307.
About Linda Vona-Davis
In an effort to advance the research mission, I actively engage faculty, residents, postgraduates and undergraduates on translational and basic science projects. I enhance the research mission by providing research training in the experimental science of cancer biology, accelerating multidisciplinary collaborations between clinical faculty and trainees, and coordinating career development activities within the Breast Cancer Research Program. My efforts assist our junior members with understanding how cancer biology and the tumor microenvironment intersect in human cancer prevention, detection, diagnosis and treatment.
In an effort to advance the education mission of our Cancer Center, I stay current on cancer biology curricula, best practices for translational training for cancer biology students and career development by serving on the Executive Board of the Cancer Biology Training Consortium who share the National Cancer Institute’s goal of producing the highest quality cancer researchers. We published a white paper on the “Essential Components of Cancer Education” in Cancer Research (PMCID: PMC4681646). I oversee the Cancer Cell Biology curriculum and coordinate annual scientific forums for pre-doctoral training.
Administratively, I direct the Biomedical Masters in Health Science Program where I oversee a 12-month, non-thesis graduate degree program designed to enhance students’ knowledge in the biomedical and public health disciplines and to help them develop and achieve their career goals.
The major theme areas to the Davis lab are: (1) Obesity and the risk and progression of breast cancer; (2) Biological factors (specifically, adipokines cytokines and growth factors) that contribute to obesity-induced dysregulation of adipocyte-tumor cell interactions; (3) Clinically relevant inflammatory targets underlying the risk of obesity and breast cancer. For over a decade, my experimental laboratory work has focused on obesity-related adipokines as mediators of cancer progression. Our lab has developed expertise using in vivo mouse models of mammary cancer (transgenic, diet-induced obesity models), to study how adipose tissue influences the metastatic potential of tumors. More recently, we have developed an interest in adipocyte biology and how cytokines and adipokines influence the breast tumor microenvironment in obesity. Our population interests are related to obesity and triple-negative breast cancer in underserved populations. We work closely with oncologists to understand breast cancer pathology, receptor status, and patterns of metastasis in Appalachia.