PO Box 9183
- MD, New York University School of Medicine
- Lucke-Wold BP, Turner RC, Logsdon AF, Bailes JE, Huber JD, Rosen CL. Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle Development. J Neurotrauma (2014 Feb 5) [Epub ahead of print]
- Turner RC, VanGilder RL, Naser ZJ, Lucke-Wold BP, Bailes JE, Matsumoto RR, Huber JD, Rosen CL. Elucidating the Severity of Preclinical Traumatic Brain Injury Models: A Role for Functional Assessment? Neurosurgery (2014 Jan 19) [Epub ahead of print]
- Tan Z, Turner RC, Leon RL, Li X, Hongpaisan J, Zheng W, Logsdon AF, Naser ZJ, Alkon DL, Rosen CL, Huber JD. Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke. Stroke (2013 Dec) 44(12): 3490-7.
- Turner RC, Naser ZJ, Logsdon AF, DiPasquale KH, Jackson GJ, Robson MJ, Gettens RT Matsumoto RR, Huber JD, Rosen CL. Modeling clinically relevant blast parameters based on scaling principles procedures functional & histological deficits in rats. Exp Neurol (2013 Oct) 248: 520-9.
- VanGilder RL, Davidov DM, Stinehart KR, Huber JD, Turner RC, Wilson KS, Haney E, Davis SM, Chantler PD, Theeke L, Rosen CL, Crocco TJ, Gutmann L, Barr TL. C-reactive protein and long-term ischemic stroke prognosis. J Clin Neurosci (2013 Aug 23) pii:S0967-5868(13)00452-9.
- Turner RC, Lucke-Wold B, Lucke-Wold N, Elliott AS, Logsdon AF, Rosen CL, Huber JD. Neuroprotection for ischemic stroke: moving past shortcomings and identifying promising directions. Int J Mol Sci (2013 Jan) 14(1): 1890-917.
- Turner RC, Dodson SC, Rosen CL, Huber JD. The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success. J Neurosurg (2013 Jan 18) [Epub ahead of print].
The neurosurgical research laboratory has three main research interests, including stroke pathophysiology, neuroprotection, and neurosurgical anatomy and cranial-base surgery approaches.
We have developed a model of embolic stroke utilizing a microcatheter and aged female rats. Our animals experience an ischemic insult and response that we believe is more representative of the clinical entity of stroke as compared to young animals challenged with filamentous occlusion. Understanding the mechanistic differences between young and old animals' ischemic injury is a major focus of our work. In addition, we have also been studying a multifunctional neuroprotective agent and how it may improve neurologic outcome following various insults. Currently we are investigating its role in cyanide toxicity and cerebral ischemia. Future studies will include subarachnoid hemorrhage and trauma. Techniques used include animal surgery, histology, and behavioral testing.
Furthermore, we also use human specimans to study microsurgical anatomy and cranial-base approaches. Operating microscopes and high speed bone dissection tools are available for studying the cranial base anatomy. Joint projects with otolaryngologists and opthalmologists are encouraged. Evaluation of new techniques and instruments are commonly performed.
Patient Care Information
- Cancer / Oncology
- Neurological Surgery, American Board of Neurological Surgery
Residency, Neurological Surgery
George Washington University Medical Center