PO Box 9193
E363, E357, WVU Eye Institute
- PhD, All India Institute of Medical Sciences, 2004
- Kolandaivelu Saravanan, Jing Huang, James B. Hurley and Visvanathan Ramamurthy 2009. AIPL1, a protein associated with childhood blindness, interacts with catalytic subunits of rod phosphodiesterase (PDE) and is essential for its assembly. J. Biol. Chem, Nov 6; 284(45):30853-61.
- Kirschman LT, Kolandaivelu S, Frederick JM, Dang L, Goldberg AF, Baehr W, Ramamurthy V. The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells. Hum Mol Genet. 2010 Mar 15;19(6):1076-87
- Christiansen JR, Kolandaivelu S, Bergo MO, Ramamurthy V. “RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments” Proc Natl Acad Sci U S A. 2011 May 24;108(21):8862-6.
- Kolandaivelu S, Chang B, Ramamurthy V. Rod Phosphodiesterase-6 (PDE6) catalytic subunits restores cone function in a mouse model lacking cone PDE6 catalytic subunit. J Biol Chem. 2011 Jul 28.
- Kolandaivelu S, Singh RK, Ramamurthy V (2013). AIPL1, A protein linked to blindness, is essential for the stability of enzymes mediating cGMP metabolism in cone photoreceptor cells. Hum Mol Genet. Oct 18. Epub ahead of print]
- Deng WT, Sakurai K, Kolandaivelu S, Kolesnikov AV, Dinculescu A, Li J, Zhu P, Liu X, Pang J, Chiodo VA, Boye SL, Chang B, Ramamurthy V, Kefalov VJ, Hauswirth WW (2013). Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse. J Neurosci. Jul 17;33 (29):11745-53.
- Anurima Majumder, Johan Pahlberg, Kimberly K Boyd, Vasily Kerov, Saravanan Kolandaivelu, Visvanathan Ramamurthy, Alapakkam P. Sampath, Nikolai Artemyev (2013). Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells. Proc. Natl. Acad. Sci.,USA. Jul 23;110 (30):12468-73.
My work has been honored and selected for an oral presentation. In addition, I have been selected for FASEB travel grant award. Title: “Post-Prenylation Processing (PPP) of proteins is needed for robust cone photo response”. FASEB (Biology and Chemistry of Vision), July 2013, Steamboat Springs, Colorado (USA).