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- West Virginia University School of Public Health
Non-Programmatically Aligned MBRCC Members
- PhD, University of Stockholm, 1981
Selected Publications (from ca. 100 total)
Knox SS. Gene x environment interactions as dynamical systems: Relevance for clinical care. Aims Mol Science 2015:3:1-11.
Knox SS, Basu S, Remick S. A systems approach to cancer health disparities in Appalachia. Austin J Public Health 2014, 1:1004. ISSN 2381-9014.
Knox SS, Funk R. Oncology and Biophysics: The need for integration. J of Clinical and Experimental Oncology. 2014:S1. doi:10.4172/2324-9110.S1-001.
Knox SS, Ochs MF. Implications of systemic dysfunction for the etiology of malignancy. Gene Regulation and Systems Biology 2013;7:11-22.
Javins B, Hobbs G, Ducatman AM, Pilkerton C, Tacker D, Knox SS. Circulating maternal perfluoroalkyl substances during pregnancy in the C8 health study. Environmental Science and Technology 2013;47:1606-13.
Stewart JC, Zielke DJ, Hawkins MAW, Williams DR, Carnethon MR, Knox SS, Matthews KA. Depressive symptom clusters and 5-year incidence of coronary artery calcification: The coronary artery risk development in young adults study. Circulation 2012;126:410-417.
Knox SS, Jackson T, Frisbee SJ, Javins B, Ducatman AM. Perfluorocarbon exposure, gender and thyroid function in the C8 Health Project. The J Toxicological Sciences, 2011;36:403-410.
Knox SS, Jackson T, Javins B, Frisbee SJ, Ducatman AM. Implications of early menopause in women exposed to perfluorocarbons. J of Clinical Endocrinology Metabolism, 96:1747-1753, 2011.
Knox SS. The elusiveness of major heart disease genes. Science 2011, Feb 10, 1148.
Knox SS, Guo X, Zhang Y, Weidner G, Williams S, Ellison RC. AGT M235T genotype / anxiety interaction and gender in the HyperGEN Study. PLoS One 2010;5:e13353.
Knox SS. From “omics” to complex disease: a systems biology approach to gene-environment interactions in cancer. Cancer Cell International 2010; 10:11.
Knox S, Wilk JB, Zhang Y, Weidner G, Ellison RC. A genome scan for hostility: The National Heart, Lung and Blood Institute Family Heart Study. Molecular Psychiatry, 2004;9:124-126.
About Sarah Knox
Dr. Sarah Knox, PhD, is a professor in the Department of Epidemiology at West Virginia University School of Public Health. She began her research career at the Karolinska Institute and University of Stockholm in Sweden, where she became an Associate Professor doing research on Swedish twins. She subsequently moved to the U.S. and the National Institutes of Health, where she did epidemiologic research at the Heart, Lung and Blood Institute, and subsequently held a leadership role in the protocol development of the National Children’s Study at the National Institute of Child Health and Human Development.
Her research has covered a broad range of topics including stress and cardiovascular disease, population genetics, systems biology, and environmental influences on human physiology. She currently has two research foci: 1) a systems biology approach to gene x environment interactions in chronic disease, (cardiovascular disease and cancer); and 2) the integration of biophysics into oncology research. She serves on the editorial board of multiple journals, and has been involved with multiple international scientific collaborations, including the Sweden / Estonia Cardiovascular Study; a U.S. – Sweden collaboration on Biobehavioral Mechanisms of Cardiovascular Disease in Women; has been a scientific advisor to a NATO Advanced Research meeting on cardiovascular disease in the East-West divide; a scientific advisor to a WHO meeting on health consequences of the long-term unemployed; and an advisor to the German Cohort Study.
Non-Programmatically Aligned Cancer Center Members