- West Virginia University School of Pharmacy
- Pharmaceutical Sciences
Program 5: Sara Crile Allen and James Frederick Allen Lung Cancer (Emerging)
- PhD, West Virginia University
Ten Most Recent:
The influence of inhaled multi-walled carbon nanotubes on the autonomic nervous system.
Zheng W, McKinney W, Kashon M, Salmen R, Castranova V, Kan H.
Part Fibre Toxicol. 2016 Feb 11;13(1):8. doi: 10.1186/s12989-016-0119-7. PMID: 26864021
Differentiation of chemical reaction activity of various carbon nanotubes using redox potential: Classification by physical and chemical structures.
Tsuruoka S, Matsumoto H, Castranova V, Porter DW, Yanagisawa T, Saito N, Kobayashi S, Endo M.
Carbon N Y. 2015 Dec;95:302-308. PMID: 26783369
Toxicological Assessment of CoO and La2O3 Metal Oxide Nanoparticles in Human Small Airway Epithelial Cells.
Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y.
Toxicol Sci. 2016 Jan 14. pii: kfw005. [Epub ahead of print] PMID: 26769336
Evaluation of the Pulmonary Toxicity of Ambient Particulate Matter From Camp Victory, Iraq.
Porter KL, Green FH, Harley RA, Vallyathan V, Castranova V, Waldron NR, Leonard SS, Nelson DE, Lewis JA, Jackson DA.
J Toxicol Environ Health A. 2015;78(23-24):1385-408. doi: 10.1080/15287394.2015.1072611. Epub 2015 Nov 23. PMID: 2659489.
Identification of TGF-β receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis.
Mishra A, Stueckle TA, Mercer RR, Derk R, Rojanasakul Y, Castranova V, Wang L.
Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L821-33. doi: 10.1152/ajplung.00002.2015. Epub 2015 Aug 21. PMID: 26472812
Silica coating influences the corona and biokinetics of cerium oxide nanoparticles.
Konduru NV, Jimenez RJ, Swami A, Friend S, Castranova V, Demokritou P, Brain JD, Molina RM.
Part Fibre Toxicol. 2015 Oct 12;12:31. doi: 10.1186/s12989-015-0106-4. PMID: 26458946
Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry.
Oberdörster G, Castranova V, Asgharian B, Sayre P.
J Toxicol Environ Health B Crit Rev. 2015;18(3-4):121-212. doi: 10.1080/10937404.2015.1051611. PMID: 26361791
Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses.
Ma J, Mercer RR, Barger M, Schwegler-Berry D, Cohen JM, Demokritou P, Castranova V.
Toxicol Appl Pharmacol. 2015 Oct 1;288(1):63-73. doi: 10.1016/j.taap.2015.07.012. Epub 2015 Jul 22. PMID: 26210349
Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.
Pirela SV, Miousse IR, Lu X, Castranova V, Thomas T, Qian Y, Bello D, Kobzik L, Koturbash I, Demokritou P.
Environ Health Perspect. 2016 Feb;124(2):210-9. doi: 10.1289/ehp.1409582. Epub 2015 Jun 16. PMID: 26080392
mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice.
Snyder-Talkington BN, Dong C, Sargent LM, Porter DW, Staska LM, Hubbs AF, Raese R, McKinney W, Chen BT, Battelli L, Lowry DT, Reynolds SH, Castranova V, Qian Y, Guo NL. J Appl Toxicol. 2016 Jan;36(1):161-74. doi: 10.1002/jat.3157. Epub 2015 Apr 29. PMID: 25926378
About Vincent Castranova
Vincent Castranova, Ph.D., was the Chief of the Pathology and Physiology Research Branch in the Health Effects Laboratory Division of the National Institute for Occupational Safety and Health, Morgantown, West Virginia and held the grade of a CDC Distinguished Consultant for a number of years until his retirement in May, 2014. He received the Shepard Lifetime Scientific Achievement Award from CDC in 2008, the Stokinger Outstanding Achievement in Industrial Toxicology Award from ACGIH in 2009, the ATS Assembly on Environmental & Occupational Health Val Vallyathan Senior Investigator Award in 2012, and the Inhalation and Respiratory Specialty Section/SOT Career Achievement Award in 2013. He is currently a professor in the Department of Pharmaceutical Sciences at West Virginia University, Morgantown, West Virginia, an adjunct professor in the Dept. of Environmental and Occupational Health at the University of Pittsburgh, and is a Visiting Scientist in the Dept. of Environmental Health at the Harvard TH Chan School of Public Health.
Dr. Castranova received a B.S. in biology from Mount Saint Mary’s College, Emmitsburg, Maryland in 1970, graduating magna cum laude. He received a Ph.D. in physiology and biophysics in 1974 from West Virginia University, Morgantown, West Virginia before becoming an NIH fellow and research faculty member in the Department of Physiology at Yale University, New Haven, Connecticut. In 1977, Dr. Castranova received a research staff position at the National Institute for Occupational Safety and Health and an adjunct faculty position at West Virginia University, Morgantown, West Virginia. He has served at these institutions since that time.
Dr. Castranova’s research interests have been concentrated in pulmonary toxicology and occupational lung disease. He was coordinator of the Nanotoxicology Program in NIOSH from its inception in 2005 until his retirement from NIOSH in 2014. He has been a co-editor of four books, has given over 165 invited presentations, and has co-authored over 690 manuscripts and book chapters.
Sara Crile Allen and James Frederick Allen Lung Cancer